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Veenstra, Siem Jakob
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1

Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors:

Veenstra, Siem Jakob ; Rueeger, Heinrich ; Voegtle, Markus...
Bioorganic & Medicinal Chemistry Letters.  28 (2018)  12 - p. 2195-2200 , 2018
Link: https://doi.org/10.1016/..
 
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2

A novel BACE inhibitor NB-360 shows a superior pharmacologi..:

Neumann, Ulf ; Rueeger, Heinrich ; Machauer, Rainer...
Molecular Neurodegeneration.  10 (2015)  1 - p. , 2015
Link: https://doi.org/10.1186/..
 
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3

Discovery of cyclic sulfoxide hydroxyethylamines as potent ..:

Rueeger, Heinrich ; Lueoend, Rainer ; Machauer, Rainer...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  19 - p. 5300-5306 , 2013
Link: https://doi.org/10.1016/..
 
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4

Discovery of Umibecestat (CNP520): A Potent, Selective, and..:

Machauer, Rainer ; Lueoend, Rainer ; Hurth, Konstanze...
Journal of Medicinal Chemistry.  64 (2021)  20 - p. 15262-15279 , 2021
Link: https://doi.org/10.1021/..
 
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5

Synthesis of the Potent, Selective, and Efficacious β-Secre..:

Rueeger, Heinrich ; Lueoend, Rainer ; Machauer, Rainer...
Journal of Medicinal Chemistry.  64 (2021)  8 - p. 4677-4696 , 2021
Link: https://doi.org/10.1021/..
 
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6

TheBACE‐1 inhibitorCNP520 for prevention trials in Alzheime..:

Neumann, Ulf ; Ufer, Mike ; Jacobson, Laura H...
EMBO Molecular Medicine.  10 (2018)  11 - p. , 2018
Link: https://doi.org/10.15252..
 
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7

Orally bioavailable Syk inhibitors with activity in a rat P..:

Thoma, Gebhard ; Veenstra, Siem ; Strang, Ross...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  20 - p. 4642-4647 , 2015
Link: https://doi.org/10.1016/..
 
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8

P4‐363: THE BACE INHIBITOR NB‐360 HAS EXCELLENT BRAIN PENET..:

Neumann, Ulf ; Rueeger, Heinrich ; Machauer, Rainer...
Alzheimer's & Dementia.  10 (2014)  4S_Part_16 - p. , 2014
Link: https://doi.org/10.1016/..
 
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9

Macrocyclic BACE-1 inhibitors acutely reduce Aβ in brain af..:

Lerchner, Andreas ; Machauer, Rainer ; Betschart, Claudia...
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  2 - p. 603-607 , 2010
Link: https://doi.org/10.1016/..
 
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10

Structure-based design and synthesis of macrocyclic peptido..:

Machauer, Rainer ; Veenstra, Siem ; Rondeau, Jean-Michel...
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  5 - p. 1361-1365 , 2009
Link: https://doi.org/10.1016/..
 
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11

Corrigendum to "Structure-based design and synthesis of mac..:

Machauer, Rainer ; Veenstra, Siem ; Rondeau, Jean-Michel...
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  8 - p. 2366 , 2009
Link: https://doi.org/10.1016/..
 
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12

Macrocyclic peptidomimetic β-secretase (BACE-1) inhibitors ..:

Machauer, Rainer ; Laumen, Kurt ; Veenstra, Siem...
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  5 - p. 1366-1370 , 2009
Link: https://doi.org/10.1016/..
 
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13

Structure-Based Design, Synthesis, and Memapsin 2 (BACE) In..:

Hanessian, Stephen ; Yun, Hongying ; Hou, Yihua...
Journal of Medicinal Chemistry.  48 (2005)  16 - p. 5175-5190 , 2005
Link: https://doi.org/10.1021/..
 
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14

Anxiolytic effect of NKP608, a NK1-receptor antagonist, in ..:

Gentsch, Conrad ; Cutler, Margaret ; Vassout, Annick..
Behavioural Brain Research.  133 (2002)  2 - p. 363-368 , 2002
Link: https://doi.org/10.1016/..
 
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15

Diastereoselective, One-Pot Synthesis of γ-Amino Alcohols f..:

Veenstra, Siem J. ; Kinderman, Sape S.
Synlett.  2001 (2001)  7 - p. 1109-1112 , 2001
Link: https://doi.org/10.1055/..
 
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