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Veenstra, Siem Jakob
26
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1
Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors:
Veenstra, Siem Jakob
;
Rueeger, Heinrich
;
Voegtle, Markus
...
Bioorganic & Medicinal Chemistry Letters. 28 (2018) 12 - p. 2195-2200 , 2018
Link:
https://doi.org/10.1016/..
?
2
A novel BACE inhibitor NB-360 shows a superior pharmacologi..:
Neumann, Ulf
;
Rueeger, Heinrich
;
Machauer, Rainer
...
Molecular Neurodegeneration. 10 (2015) 1 - p. , 2015
Link:
https://doi.org/10.1186/..
?
3
Discovery of cyclic sulfoxide hydroxyethylamines as potent ..:
Rueeger, Heinrich
;
Lueoend, Rainer
;
Machauer, Rainer
...
Bioorganic & Medicinal Chemistry Letters. 23 (2013) 19 - p. 5300-5306 , 2013
Link:
https://doi.org/10.1016/..
?
4
Discovery of Umibecestat (CNP520): A Potent, Selective, and..:
Machauer, Rainer
;
Lueoend, Rainer
;
Hurth, Konstanze
...
Journal of Medicinal Chemistry. 64 (2021) 20 - p. 15262-15279 , 2021
Link:
https://doi.org/10.1021/..
?
5
Synthesis of the Potent, Selective, and Efficacious β-Secre..:
Rueeger, Heinrich
;
Lueoend, Rainer
;
Machauer, Rainer
...
Journal of Medicinal Chemistry. 64 (2021) 8 - p. 4677-4696 , 2021
Link:
https://doi.org/10.1021/..
?
6
TheBACE‐1 inhibitorCNP520 for prevention trials in Alzheime..:
Neumann, Ulf
;
Ufer, Mike
;
Jacobson, Laura H
...
EMBO Molecular Medicine. 10 (2018) 11 - p. , 2018
Link:
https://doi.org/10.15252..
?
7
Orally bioavailable Syk inhibitors with activity in a rat P..:
Thoma, Gebhard
;
Veenstra, Siem
;
Strang, Ross
...
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 20 - p. 4642-4647 , 2015
Link:
https://doi.org/10.1016/..
?
8
P4‐363: THE BACE INHIBITOR NB‐360 HAS EXCELLENT BRAIN PENET..:
Neumann, Ulf
;
Rueeger, Heinrich
;
Machauer, Rainer
...
Alzheimer's & Dementia. 10 (2014) 4S_Part_16 - p. , 2014
Link:
https://doi.org/10.1016/..
?
9
Macrocyclic BACE-1 inhibitors acutely reduce Aβ in brain af..:
Lerchner, Andreas
;
Machauer, Rainer
;
Betschart, Claudia
...
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 2 - p. 603-607 , 2010
Link:
https://doi.org/10.1016/..
?
10
Structure-based design and synthesis of macrocyclic peptido..:
Machauer, Rainer
;
Veenstra, Siem
;
Rondeau, Jean-Michel
...
Bioorganic & Medicinal Chemistry Letters. 19 (2009) 5 - p. 1361-1365 , 2009
Link:
https://doi.org/10.1016/..
?
11
Corrigendum to "Structure-based design and synthesis of mac..:
Machauer, Rainer
;
Veenstra, Siem
;
Rondeau, Jean-Michel
...
Bioorganic & Medicinal Chemistry Letters. 19 (2009) 8 - p. 2366 , 2009
Link:
https://doi.org/10.1016/..
?
12
Macrocyclic peptidomimetic β-secretase (BACE-1) inhibitors ..:
Machauer, Rainer
;
Laumen, Kurt
;
Veenstra, Siem
...
Bioorganic & Medicinal Chemistry Letters. 19 (2009) 5 - p. 1366-1370 , 2009
Link:
https://doi.org/10.1016/..
?
13
Structure-Based Design, Synthesis, and Memapsin 2 (BACE) In..:
Hanessian, Stephen
;
Yun, Hongying
;
Hou, Yihua
...
Journal of Medicinal Chemistry. 48 (2005) 16 - p. 5175-5190 , 2005
Link:
https://doi.org/10.1021/..
?
14
Anxiolytic effect of NKP608, a NK1-receptor antagonist, in ..:
Gentsch, Conrad
;
Cutler, Margaret
;
Vassout, Annick
..
Behavioural Brain Research. 133 (2002) 2 - p. 363-368 , 2002
Link:
https://doi.org/10.1016/..
?
15
Diastereoselective, One-Pot Synthesis of γ-Amino Alcohols f..:
Veenstra, Siem J.
;
Kinderman, Sape S.
Synlett. 2001 (2001) 7 - p. 1109-1112 , 2001
Link:
https://doi.org/10.1055/..
1-15