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Volgraf, Matthew
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1

Discovery and Optimization of Selective Brain-Penetrant EBP..:

Dorel, Ruth ; Sun, Dawei ; Carruthers, Nicholas...
Journal of Medicinal Chemistry.  67 (2024)  6 - p. 4819-4832 , 2024
Link: https://doi.org/10.1021/..
 
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2

Cryo-EM reveals an unprecedented binding site for NaV1.7 in..:

Jao, Christine C ; Kschonsak, Marc ; Arthur, Christopher P...
eLife.  12 (2023)  - p. , 2023
Link: https://doi.org/10.7554/..
 
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3

A Retrospective Look at the Impact of Binding Site Environm..:

Villemure, Elisia ; Terrett, Jack A. ; Larouche-Gauthier, Robin...
ACS Medicinal Chemistry Letters.  12 (2021)  8 - p. 1230-1237 , 2021
Link: https://doi.org/10.1021/..
 
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4

A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 I..:

Liu, Chang ; Reese, Rebecca ; Vu, Simon...
Neuron.  109 (2021)  2 - p. 273-284.e4 , 2021
Link: https://doi.org/10.1016/..
 
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5

Ligand binding at the protein–lipid interface: strategic co..:

Payandeh, Jian ; Volgraf, Matthew
Nature Reviews Drug Discovery.  20 (2021)  9 - p. 710-722 , 2021
Link: https://doi.org/10.1038/..
 
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6

GluN2A NMDA Receptor Enhancement Improves Brain Oscillation..:

Hanson, Jesse E. ; Ma, Keran ; Elstrott, Justin...
Cell Reports.  30 (2020)  2 - p. 381-396.e4 , 2020
Link: https://doi.org/10.1016/..
 
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7

TRPA1 modulation by piperidine carboxamides suggests an evo..:

Chernov-Rogan, Tania ; Gianti, Eleonora ; Liu, Chang...
Proceedings of the National Academy of Sciences.  116 (2019)  51 - p. 26008-26019 , 2019
Link: https://doi.org/10.1073/..
 
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8

TRPA1 modulation by piperidine carboxamides suggests an evo..:

Chernov-Rogan, Tania ; Gianti, Eleonora ; Liu, Chang...
Proceedings of the National Academy of Sciences of the United States of America.  116 (2019)  51 - p. 26008-26019 , 2019
Link: https://www.jstor.org/st..
 
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9

Discovery of a Potent (4R,5S)-4-Fluoro-5-methylproline Sulf..:

Chen, Huifen ; Volgraf, Matthew ; Do, Steven...
Journal of Medicinal Chemistry.  61 (2018)  8 - p. 3641-3659 , 2018
Link: https://doi.org/10.1021/..
 
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10

A novel NMDA receptor positive allosteric modulator that ac..:

Wang, Tzu-Ming ; Brown, Brandon M. ; Deng, Lunbin...
Neuropharmacology.  121 (2017)  - p. 204-218 , 2017
Link: https://doi.org/10.1016/..
 
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11

Discovery of 5-Azaindazole (GNE-955) as a Potent Pan-Pim In..:

Wang, Xiaojing ; Kolesnikov, Aleksandr ; Tay, Suzanne...
Journal of Medicinal Chemistry.  60 (2017)  10 - p. 4458-4473 , 2017
Link: https://doi.org/10.1021/..
 
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12

Discovery of GluN2A-Selective NMDA Receptor Positive Allost..:

Volgraf, Matthew ; Sellers, Benjamin D. ; Jiang, Yu...
Journal of Medicinal Chemistry.  59 (2016)  6 - p. 2760-2779 , 2016
Link: https://doi.org/10.1021/..
 
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13

GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positiv..:

Villemure, Elisia ; Volgraf, Matthew ; Jiang, Yu...
ACS Medicinal Chemistry Letters.  8 (2016)  1 - p. 84-89 , 2016
Link: https://doi.org/10.1021/..
 
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14

Positive Allosteric Modulators of GluN2A-Containing NMDARs ..:

Hackos, David H. ; Lupardus, Patrick J. ; Grand, Teddy...
Neuron.  89 (2016)  5 - p. 983-999 , 2016
Link: https://doi.org/10.1016/..
 
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15

Synthesis, characterization, and PK/PD studies of a series ..:

Volgraf, Matthew ; Chan, Lina ; Huestis, Malcolm P....
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  11 - p. 2477-2480 , 2014
Link: https://doi.org/10.1016/..
 
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