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Willis, Nicky J.
53
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Online (53)
Mediatypes
Articles (Online) (29)
OpenAccess-fulltext (24)
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1
Designed switch from covalent to non-covalent inhibitors of..:
Atkinson, Benjamin N.
;
Willis, Nicky J.
;
Zhao, Yuguang
...
European Journal of Medicinal Chemistry. 251 (2023) - p. 115132 , 2023
Link:
https://doi.org/10.1016/..
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2
Structural Analysis and Development of Notum Fragment Scree..:
Zhao, Yuguang
;
Mahy, William
;
Willis, Nicky J.
...
ACS Chemical Neuroscience. 13 (2022) 13 - p. 2060-2077 , 2022
Link:
https://doi.org/10.1021/..
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3
Structure-activity relationships of 2-pyrimidinecarbohydraz..:
Chatzopoulou, Maria
;
Conole, Daniel
;
Emer, Enrico
...
Bioorganic & Medicinal Chemistry. 69 (2022) - p. 116812 , 2022
Link:
https://doi.org/10.1016/..
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4
Large-scale synthesis of Notum inhibitor 1-(2,4-dichloro-3-..:
Atkinson, Benjamin N.
;
Willis, Nicky J.
;
Smith, Jennifer
...
RSC Advances. 12 (2022) 41 - p. 26497-26503 , 2022
Link:
https://doi.org/10.1039/..
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5
Design of a Potent, Selective, and Brain-Penetrant Inhibito..:
Willis, Nicky J.
;
Mahy, William
;
Sipthorp, James
...
Journal of Medicinal Chemistry. 65 (2022) 10 - p. 7212-7230 , 2022
Link:
https://doi.org/10.1021/..
?
6
Discovery and mechanism of action studies of 4,6-diphenylpy..:
Vuorinen, Aini
;
Wilkinson, Isabel V.L.
;
Chatzopoulou, Maria
...
European Journal of Medicinal Chemistry. 220 (2021) - p. 113431 , 2021
Link:
https://doi.org/10.1016/..
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7
Virtual Screening Directly Identifies New Fragment-Sized In..:
Steadman, David
;
Atkinson, Benjamin N.
;
Zhao, Yuguang
...
Journal of Medicinal Chemistry. 65 (2021) 1 - p. 562-578 , 2021
Link:
https://doi.org/10.1021/..
?
8
Structural Requirements for Dihydrobenzoxazepinone Anthelmi..:
Partridge, Frederick A.
;
Bataille, Carole J.R.
;
Forman, Ruth
...
ACS Infectious Diseases. 7 (2021) 5 - p. 1260-1274 , 2021
Link:
https://doi.org/10.1021/..
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9
Carboxylesterase Notum Is a Druggable Target to Modulate Wn..:
Bayle, Elliott D.
;
Svensson, Fredrik
;
Atkinson, Benjamin N.
...
Journal of Medicinal Chemistry. 64 (2021) 8 - p. 4289-4311 , 2021
Link:
https://doi.org/10.1021/..
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10
NOTUM from Apc-mutant cells biases clonal competition to in..:
Flanagan, Dustin J.
;
Pentinmikko, Nalle
;
Luopajärvi, Kalle
...
Nature. 594 (2021) 7863 - p. 430-435 , 2021
Link:
https://doi.org/10.1038/..
?
11
Screening of a Custom-Designed Acid Fragment Library Identi..:
Mahy, William
;
Patel, Mikesh
;
Steadman, David
...
Journal of Medicinal Chemistry. 63 (2020) 17 - p. 9464-9483 , 2020
Link:
https://doi.org/10.1021/..
?
12
5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors o..:
Mahy, William
;
Willis, Nicky J.
;
Zhao, Yuguang
...
Journal of Medicinal Chemistry. 63 (2020) 21 - p. 12942-12956 , 2020
Link:
https://doi.org/10.1021/..
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13
Isolation, Structural Identification, Synthesis, and Pharma..:
Chatzopoulou, Maria
;
Claridge, Tim D. W.
;
Davies, Kay E.
...
Journal of Medicinal Chemistry. 63 (2019) 5 - p. 2547-2556 , 2019
Link:
https://doi.org/10.1021/..
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14
An improved, scalable synthesis of Notum inhibitor LP-92205..:
Willis, Nicky J
;
Bayle, Elliott D
;
Papageorgiou, George
...
Beilstein Journal of Organic Chemistry. 15 (2019) - p. 2790-2797 , 2019
Link:
https://doi.org/10.3762/..
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15
An automated high-throughput system for phenotypic screenin..:
Partridge, Frederick A.
;
Brown, Anwen E.
;
Buckingham, Steven D.
...
International Journal for Parasitology: Drugs and Drug Resistance. 8 (2018) 1 - p. 8-21 , 2018
Link:
https://doi.org/10.1016/..
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