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Winter-Holt, Jon J.
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1

Fragment-Based Discovery of Novel MUS81 Inhibitors:

Collie, Gavin W. ; Börjesson, Ulf ; Chen, Yunhua...
ACS Medicinal Chemistry Letters.  15 (2024)  7 - p. 1151-1158 , 2024
Link: https://doi.org/10.1021/..
 
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2

Identification and Strategies to Mitigate High Total Cleara..:

Williamson, Beth ; McMurray, Lindsay ; Boyd, Scott...
Molecular Pharmaceutics.  19 (2022)  7 - p. 2115-2132 , 2022
Link: https://doi.org/10.1021/..
 
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3

Pharmacological inhibition of MERTK induces in vivo retinal..:

Hamm, Gregory ; Maglennon, Gareth ; Williamson, Beth...
Archives of Toxicology.  96 (2022)  2 - p. 613-624 , 2022
Link: https://doi.org/10.1007/..
 
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4

Discovery of a Potent and Selective ATAD2 Bromodomain Inhib..:

Winter-Holt, Jon J. ; Bardelle, Catherine ; Chiarparin, Elisabetta...
Journal of Medicinal Chemistry.  65 (2022)  4 - p. 3306-3331 , 2022
Link: https://doi.org/10.1021/..
 
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5

Generating Selective Leads for Mer Kinase Inhibitors—Exampl..:

Nissink, J. Willem M. ; Bazzaz, Sana ; Blackett, Carolyn...
Journal of Medicinal Chemistry.  64 (2021)  6 - p. 3165-3184 , 2021
Link: https://doi.org/10.1021/..
 
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6

Discovery of (2R)-N-[3-[2-[(3-Methoxy-1-methyl-pyrazol-4-yl..:

Su, Qibin ; Banks, Erica ; Bebernitz, Geraldine...
Journal of Medicinal Chemistry.  63 (2020)  9 - p. 4517-4527 , 2020
Link: https://doi.org/10.1021/..
 
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7

A-loop interactions in Mer tyrosine kinase give rise to inh..:

Pflug, Alexander ; Schimpl, Marianne ; Nissink, J. Willem M....
Biochemical Journal.  477 (2020)  22 - p. 4443-4452 , 2020
Link: https://doi.org/10.1042/..
 
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8

A High-Throughput Screening Triage Workflow to Authenticate..:

St-Gallay, Stephen A. ; Bennett, Neil ; Critchlow, Susan E....
SLAS Discovery.  23 (2018)  1 - p. 11-22 , 2018
Link: https://doi.org/10.1177/..
 
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9

MTH1 Substrate Recognition—An Example of Specific Promiscui..:

Nissink, J. Willem M. ; Bista, Michal ; Breed, Jason...
PLOS ONE.  11 (2016)  3 - p. e0151154 , 2016
Link: https://doi.org/10.1371/..
 
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10

Pharmacological inhibition of MERTK induces in vivo retinal..:

Hamm, Gregory ; Maglennon, Gareth ; Williamson, Beth...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837544/.  , 2022
Link: http://www.ncbi.nlm.nih...
 
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11

The structure of human GCN2 reveals a parallel, back-to-bac..:

Maia de Oliveira, Taiana ; Korboukh, Victoria ; Caswell, Sarah...
Biochemical Journal.  477 (2020)  1 - p. 275-284 , 2020
Link: https://doi.org/10.1042/..
 
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12

A-loop interactions in Mer tyrosine kinase give rise to inh..:

Pflug, Alexander ; Schimpl, Marianne ; Nissink, J. Willem M...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702301/.  , 2020
Link: http://www.ncbi.nlm.nih...
 
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13

MTH1 Substrate Recognition--An Example of Specific Promiscu..:

J Willem M Nissink ; Michal Bista ; Jason Breed...
http://europepmc.org/articles/PMC4801406?pdf=render.  , 2016
Link: https://doi.org/10.1371/..
 
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14

Optimization of an Imidazo[1,2‑ a ]pyridine Series to Affor..:

William McCoull (1763365) ; Scott Boyd (1299897) ; Martin R. Brown (3368084)...
https://figshare.com/articles/journal_contribution/Optimization_of_an_Imidazo_1_2_i_a_i_pyridine_Series_to_Afford_Highly_Selective_Type_I1_2_Dual_Mer_Axl_Kinase_Inhibitors_with_i_In_Vivo_i_Efficacy/16569147.  , 2021
Link: https://doi.org/10.1021/..
 
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15

Optimization of an Imidazo[1,2‑ a ]pyridine Series to Affor..:

William McCoull (1763365) ; Scott Boyd (1299897) ; Martin R. Brown (3368084)...
https://figshare.com/articles/dataset/Optimization_of_an_Imidazo_1_2_i_a_i_pyridine_Series_to_Afford_Highly_Selective_Type_I1_2_Dual_Mer_Axl_Kinase_Inhibitors_with_i_In_Vivo_i_Efficacy/16569150.  , 2021
Link: https://doi.org/10.1021/..
 
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