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Wittman, Mark D.
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1

Discovery of Orally Active Isofuranones as Potent, Selectiv..:

Degnan, Andrew P. ; Kumi, Godwin K. ; Allard, Christopher W....
ACS Medicinal Chemistry Letters.  12 (2021)  3 - p. 443-450 , 2021
Link: https://doi.org/10.1021/..
 
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2

Enhanced antitumor immunity by a novel small molecule HPK1 ..:

You, Dan ; Hillerman, Stephen ; Locke, Gregory...
Journal for ImmunoTherapy of Cancer.  9 (2021)  1 - p. e001402 , 2021
Link: https://doi.org/10.1136/..
 
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3

Biochemical and transcriptional profiling to triage additio..:

Ross-Macdonald, Petra ; de Silva, Heshani ; Patel, Vishal...
Bioorganic & Medicinal Chemistry.  20 (2012)  6 - p. 1961-1972 , 2012
Link: https://doi.org/10.1016/..
 
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4

SAR of PXR transactivation in benzimidazole-based IGF-1R ki..:

Zimmermann, Kurt ; Wittman, Mark D. ; Saulnier, Mark G....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  5 - p. 1744-1748 , 2010
Link: https://doi.org/10.1016/..
 
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5

Insulin-like growth factor-1 receptor (IGF-1R) kinase inhib..:

Velaparthi, Upender ; Saulnier, Mark G. ; Wittman, Mark D....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  10 - p. 3182-3185 , 2010
Link: https://doi.org/10.1016/..
 
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6

Proline isosteres in a series of 2,4-disubstituted pyrrolo[..:

Sampognaro, Anthony J. ; Wittman, Mark D. ; Carboni, Joan M....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  17 - p. 5027-5030 , 2010
Link: https://doi.org/10.1016/..
 
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7

Discovery of a 2,4-Disubstituted Pyrrolo[1,2-f][1,2,4]triaz..:

Wittman, Mark D. ; Carboni, Joan M. ; Yang, Zheng...
Journal of Medicinal Chemistry.  52 (2009)  23 - p. 7360-7363 , 2009
Link: https://doi.org/10.1021/..
 
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8

2-(1H-Imidazol-4-yl)ethanamine and 2-(1H-pyrazol-1-yl)ethan..:

Saulnier, Mark G. ; Frennesson, David B. ; Wittman, Mark D....
Bioorganic & Medicinal Chemistry Letters.  18 (2008)  5 - p. 1702-1707 , 2008
Link: https://doi.org/10.1016/..
 
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9

Balancing oral exposure with Cyp3A4 inhibition in benzimida..:

Zimmermann, Kurt ; Wittman, Mark D. ; Saulnier, Mark G....
Bioorganic & Medicinal Chemistry Letters.  18 (2008)  14 - p. 4075-4080 , 2008
Link: https://doi.org/10.1016/..
 
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10

Discovery and Evaluation of 4-(2-(4-chloro-1H-pyrazol-1-yl)..:

Velaparthi, Upender ; Wittman, Mark ; Liu, Peiying...
Journal of Medicinal Chemistry.  51 (2008)  19 - p. 5897-5900 , 2008
Link: https://doi.org/10.1021/..
 
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11

Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)py..:

Velaparthi, Upender ; Wittman, Mark ; Liu, Peiying...
Bioorganic & Medicinal Chemistry Letters.  17 (2007)  8 - p. 2317-2321 , 2007
Link: https://doi.org/10.1016/..
 
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12

Novel 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of..:

Wittman, Mark D. ; Balasubramanian, Balu ; Stoffan, Karen...
Bioorganic & Medicinal Chemistry Letters.  17 (2007)  4 - p. 974-977 , 2007
Link: https://doi.org/10.1016/..
 
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13

Imidazole moiety replacements in the 3-(1H-benzo[d]imidazol..:

Velaparthi, Upender ; Liu, Peiying ; Balasubramanian, Balu...
Bioorganic & Medicinal Chemistry Letters.  17 (2007)  11 - p. 3072-3076 , 2007
Link: https://doi.org/10.1016/..
 
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14

Discovery of a 1H-Benzoimidazol-2-yl)-1H-pyridin-2-one (BMS..:

Wittman, Mark ; Carboni, Joan ; Attar, Ricardo...
Journal of Medicinal Chemistry.  48 (2005)  18 - p. 5639-5643 , 2005
Link: https://doi.org/10.1021/..
 
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15

Microwave-assisted synthesis of primary amine HX salts from..:

Saulnier, Mark G. ; Zimmermann, Kurt ; Struzynski, Charles P....
Tetrahedron Letters.  45 (2004)  2 - p. 397-399 , 2004
Link: https://doi.org/10.1016/..
 
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