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Xu, Zangwei
29  results:
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1

Discovery of MK-1084: An Orally Bioavailable and Low-Dose K..:

Ma, Xiaoshen ; Sloman, David L. ; Duggal, Ruchia...
Journal of Medicinal Chemistry.  67 (2024)  13 - p. 11024-11052 , 2024
Link: https://doi.org/10.1021/..
 
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2

Identification of Potent Reverse Indazole Inhibitors for HP..:

Yu, Elsie C. ; Methot, Joey L. ; Fradera, Xavier...
ACS Medicinal Chemistry Letters.  12 (2021)  3 - p. 459-466 , 2021
Link: https://doi.org/10.1021/..
 
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3

Development of High-Throughput Assays for Evaluation of Hem..:

Lacey, Brian M. ; Xu, Zangwei ; Chai, Xiaomei...
SLAS Discovery.  26 (2021)  1 - p. 88-99 , 2021
Link: https://doi.org/10.1177/..
 
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4

Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors ..:

Vara, Brandon A. ; Levi, Samuel M. ; Achab, Abdelghani...
ACS Medicinal Chemistry Letters.  12 (2021)  4 - p. 653-661 , 2021
Link: https://doi.org/10.1021/..
 
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5

Allosteric Modulation of Protein Arginine Methyltransferase..:

Palte, Rachel L. ; Schneider, Sebastian E. ; Altman, Michael D....
ACS Medicinal Chemistry Letters.  11 (2020)  9 - p. 1688-1693 , 2020
Link: https://doi.org/10.1021/..
 
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6

Pharmacological inhibition of hematopoietic progenitor kina..:

Wang, Yun ; Zhang, Kelvin ; Georgiev, Peter...
PLOS ONE.  15 (2020)  12 - p. e0243145 , 2020
Link: https://doi.org/10.1371/..
 
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7

Potent, non-covalent reversible BTK inhibitors with 8-amino..:

Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto...
Bioorganic & Medicinal Chemistry Letters.  30 (2020)  17 - p. 127390 , 2020
Link: https://doi.org/10.1016/..
 
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8

Discovery of novel BTK inhibitors with carboxylic acids:

Gao, Xiaolei ; Wang, James ; Liu, Jian...
Bioorganic & Medicinal Chemistry Letters.  27 (2017)  6 - p. 1471-1477 , 2017
Link: https://doi.org/10.1016/..
 
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9

Discovery of 3-morpholino-imidazole[1,5-a]pyrazine BTK inhi..:

Boga, Sobhana Babu ; Alhassan, Abdul-Basit ; Liu, Jian...
Bioorganic & Medicinal Chemistry Letters.  27 (2017)  16 - p. 3939-3943 , 2017
Link: https://doi.org/10.1016/..
 
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10

Integration of Affinity Selection–Mass Spectrometry and Fun..:

Kutilek, Victoria D. ; Andrews, Christine L. ; Richards, Matthew P....
SLAS Discovery.  21 (2016)  6 - p. 608-619 , 2016
Link: https://doi.org/10.1177/..
 
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11

Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible ..:

Liu, Jian ; Guiadeen, Deodial ; Krikorian, Arto...
ACS Medicinal Chemistry Letters.  7 (2015)  2 - p. 198-203 , 2015
Link: https://doi.org/10.1021/..
 
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12

Genetic and Pharmacological Inhibition of PDK1 in Cancer Ce..:

Nagashima, Kumiko ; Shumway, Stuart D. ; Sathyanarayanan, Sriram...
Journal of Biological Chemistry.  286 (2011)  8 - p. 6433-6448 , 2011
Link: https://doi.org/10.1074/..
 
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13

Identification of Direct Target Engagement Biomarkers for K..:

Paweletz, Cloud P. ; Andersen, Jannik N. ; Pollock, Roy...
PLoS ONE.  6 (2011)  10 - p. e26459 , 2011
Link: https://doi.org/10.1371/..
 
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14

Discovery of PDK1 Kinase Inhibitors with a Novel Mechanism ..:

Bobkova, Ekaterina V. ; Weber, Michael J. ; Xu, Zangwei...
Journal of Biological Chemistry.  285 (2010)  24 - p. 18838-18846 , 2010
Link: https://doi.org/10.1074/..
 
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15

Development of High-Throughput TR-FRET and AlphaScreen® Ass..:

Xu, Zangwei ; Nagashima, Kumiko ; Sun, Dongyu...
SLAS Discovery.  14 (2009)  10 - p. 1257-1262 , 2009
Link: https://doi.org/10.1177/..
 
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