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de Lera Ruiz, Manuel
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1

Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor E..:

Shurtleff, Valerie W. ; Layton, Mark E. ; Parish, Craig A....
Journal of Medicinal Chemistry.  67 (2024)  5 - p. 3935-3958 , 2024
Link: https://doi.org/10.1021/..
 
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2

Basis for drug selectivity of plasmepsin IX and X inhibitio..:

Hodder, Anthony N. ; Christensen, Janni ; Scally, Stephen...
Structure.  30 (2022)  7 - p. 947-961.e6 , 2022
Link: https://doi.org/10.1016/..
 
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3

The Invention of WM382, a Highly Potent PMIX/X Dual Inhibit..:

de Lera Ruiz, Manuel ; Favuzza, Paola ; Guo, Zhuyan...
ACS Medicinal Chemistry Letters.  13 (2022)  11 - p. 1745-1754 , 2022
Link: https://doi.org/10.1021/..
 
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4

Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multi..:

Favuzza, Paola ; de Lera Ruiz, Manuel ; Thompson, Jennifer K....
Cell Host & Microbe.  27 (2020)  4 - p. 642-658.e12 , 2020
Link: https://doi.org/10.1016/..
 
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5

Synthesis of a CGRP Receptor Antagonist via an Asymmetric S..:

Molinaro, Carmela ; Phillips, Eric M. ; Xiang, Bangping...
The Journal of Organic Chemistry.  84 (2019)  12 - p. 8006-8018 , 2019
Link: https://doi.org/10.1021/..
 
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6

Careful Navigation of the Crystallographic Landscape of MK-..:

Tsou, Nancy ; Shultz, C. Scott ; Andreani, Teresa...
Organic Process Research & Development.  19 (2015)  12 - p. 1882-1890 , 2015
Link: https://doi.org/10.1021/..
 
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7

Voltage-Gated Sodium Channels: Structure, Function, Pharmac..:

de Lera Ruiz, Manuel ; Kraus, Richard L.
Journal of Medicinal Chemistry.  58 (2015)  18 - p. 7093-7118 , 2015
Link: https://doi.org/10.1021/..
 
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8

Adenosine A2A Receptor as a Drug Discovery Target:

de Lera Ruiz, Manuel ; Lim, Yeon-Hee ; Zheng, Junying
Journal of Medicinal Chemistry.  57 (2013)  9 - p. 3623-3650 , 2013
Link: https://doi.org/10.1021/..
 
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9

Bicyclic and tricyclic heterocycle derivatives as histamine..:

de Lera Ruiz, Manuel ; Zheng, Junying ; Berlin, Michael Y....
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  21 - p. 6004-6009 , 2013
Link: https://doi.org/10.1016/..
 
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10

Histamine H3 Receptor as a Drug Discovery Target:

Berlin, Michael ; Boyce, Christopher W. ; de Lera Ruiz, Manuel
Journal of Medicinal Chemistry.  54 (2010)  1 - p. 26-53 , 2010
Link: https://doi.org/10.1021/..
 
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11

Evaluation of possible intramolecular [4+2] cycloaddition r..:

Pichlmair, Stefan ; de Lera Ruiz, Manuel ; Basu, Kallol.
Tetrahedron.  62 (2006)  22 - p. 5178-5194 , 2006
Link: https://doi.org/10.1016/..
 
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12

Exploration of conjugate addition routes to advanced tricyc..:

Pichlmair, Stefan ; de Lera Ruiz, Manuel ; Vilotijevic, Ivan.
Tetrahedron.  62 (2006)  24 - p. 5791-5802 , 2006
Link: https://doi.org/10.1016/..
 
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13

Stereoselective synthesis of highly functionalised P-stereo..:

Whittaker, Benjamin ; Ruiz, Manuel de Lera ; Hayes, Christopher J.
Tetrahedron Letters.  49 (2008)  49 - p. 6984-6987 , 2008
Link: https://doi.org/10.1016/..
 
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14

Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multi..:

Favuzza, Paola ; de Lera Ruiz, Manuel ; Thompson, Jennifer K...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146544/.  , 2020
Link: http://www.ncbi.nlm.nih...
 
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15

CPR integral program implementation in a 3rd level hospital:

Fernández, Camilo González ; Borregán, Juan Carlos Rodríguez ; Suescun, Antonio Quesada...
Resuscitation.  85 (2014)  - p. S87 , 2014
Link: https://doi.org/10.1016/..
 
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