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Multivariate Hypergeometric Similarity Measure:

Kaddi, Chanchala D. ; Parry, R. Mitchell ; Wang, May D.
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB).  10 (2013)  6 - p. 1505-1516 , 2013
Link: https://dl.acm.org/doi/10.1109/TCBB.2013.28