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Destabilizers of the thymidylate synthase homodimer acceler..:
Costantino, Luca
;
Ferrari, Stefania
;
Santucci, Matteo
...
qt4vr606hw. , 2022
Link:
https://escholarship.org/uc/item/4vr606hw
RT Journal T1
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth
UL https://suche.suub.uni-bremen.de/peid=base-ftcdlib:oai:escholarship.org:ark:_13030_qt4vr606hw&Exemplar=1&LAN=DE A1 Costantino, Luca A1 Ferrari, Stefania A1 Santucci, Matteo A1 Salo-Ahen, Outi MH A1 Carosati, Emanuele A1 Franchini, Silvia A1 Lauriola, Angela A1 Pozzi, Cecilia A1 Trande, Matteo A1 Gozzi, Gaia A1 Saxena, Puneet A1 Cannazza, Giuseppe A1 Losi, Lorena A1 Cardinale, Daniela A1 Venturelli, Alberto A1 Quotadamo, Antonio A1 Linciano, Pasquale A1 Tagliazucchi, Lorenzo A1 Moschella, Maria Gaetana A1 Guerrini, Remo A1 Pacifico, Salvatore A1 Luciani, Rosaria A1 Genovese, Filippo A1 Henrich, Stefan A1 Alboni, Silvia A1 Santarem, Nuno A1 da Silva Cordeiro, Anabela A1 Giovannetti, Elisa A1 Peters, Godefridus J A1 Pinton, Paolo A1 Rimessi, Alessandro A1 Cruciani, Gabriele A1 Stroud, Robert M A1 Wade, Rebecca C A1 Mangani, Stefano A1 Marverti, Gaetano A1 D'Arca, Domenico A1 Ponterini, Glauco A1 Costi, Maria Paola PB eScholarship, University of California YR 2022 K1 Biochemistry and Cell Biology K1 Biomedical and Clinical Sciences K1 Oncology and Carcinogenesis K1 Biological Sciences K1 Cancer K1 Orphan Drug K1 Rare Diseases K1 Biotechnology K1 Development of treatments and therapeutic interventions K1 5.1 Pharmaceuticals K1 Female K1 Animals K1 Mice K1 Humans K1 Binding Sites K1 Thymidylate Synthase K1 Fluorouracil K1 Ovarian Neoplasms K1 Enzyme Inhibitors K1 protein dimer destabilizers K1 cancer growth inhibition K1 proteasomal degradation K1 enzyme dissociative inhibition mechanism K1 target engagement K1 Human K1 biochemistry K1 cancer biology K1 chemical biology K1 Health sciences JF qt4vr606hw LK http://dx.doi.org/https://escholarship.org/uc/item/4vr606hw DO https://escholarship.org/uc/item/4vr606hw SF ELIB - SuUB Bremen
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