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Discovery of Novel 8‑Hydroxyquinoline Derivatives with Pote..:
Liping Li
;
Hao Wu
;
Jiayin Wang
...
doi:10.1021/acs.jmedchem.3c01771.s002. , 2023
Link:
https://doi.org/10.1021/acs.jmedchem.3c01771.s002
RT Journal T1
Discovery of Novel 8‑Hydroxyquinoline Derivatives with Potent In Vitro and In Vivo Antifungal Activity
UL https://suche.suub.uni-bremen.de/peid=base-ftdeakinunifig:oai:figshare.com:article_24582498&Exemplar=1&LAN=DE A1 Liping Li A1 Hao Wu A1 Jiayin Wang A1 Zhe Ji A1 Ting Fang A1 Hui Lu A1 Lan Yan A1 Fuming Shen A1 Dazhi Zhang A1 Yuanying Jiang A1 Tingjunhong Ni YR 2023 K1 Biochemistry K1 Medicine K1 Microbiology K1 Pharmacology K1 Biotechnology K1 Ecology K1 Immunology K1 Cancer K1 Infectious Diseases K1 Plant Biology K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 yet current antifungals K1 report hit compound K1 reducing fungal burden K1 acceptable safety profiles K1 spectrum antifungal activity K1 significant inhibitory activity K1 infected murine model K1 kg showed better K1 novel drug discovery K1 l14 </ b K1 better activity K1 showed synergy K1 infected mice K1 vivo </ K1 vitro </ K1 treating many K1 threatening infections K1 novel 8 K1 lower cytotoxicity K1 hydroxyquinoline derivative K1 favorable pharmacokinetics K1 experiments exhibited K1 data indicated K1 cause life K1 biofilm formation K1 2 mg JF doi:10.1021/acs.jmedchem.3c01771.s002 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.3c01771.s002 DO https://doi.org/10.1021/acs.jmedchem.3c01771.s002 SF ELIB - SuUB Bremen
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