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1 Ergebnisse
1
A Novel Bifunctional μOR Agonist and σ 1 R Antagonist with ..:
Zhuang Miao
;
Yuhan Zhong
;
Yu Gan
...
doi:10.1021/acs.jmedchem.3c01637.s001. , 2023
Link:
https://doi.org/10.1021/acs.jmedchem.3c01637.s001
RT Journal T1
A Novel Bifunctional μOR Agonist and σ 1 R Antagonist with Potent Analgesic Responses and Reduced Adverse Effects
UL https://suche.suub.uni-bremen.de/peid=base-ftdeakinunifig:oai:figshare.com:article_24653011&Exemplar=1&LAN=DE A1 Zhuang Miao A1 Yuhan Zhong A1 Yu Gan A1 Kequan Fu A1 Wencheng Liu A1 Zhihua Cao A1 Tiantian Zhao A1 Ziyuan Li A1 Ao Hai A1 Yanlai Peng A1 Zeping Zuo A1 Tian Zhang A1 Shilong Hu A1 Chunxia Chen A1 Ting Kang A1 Tianguang Huang A1 Dong Guo A1 Bowen Ke YR 2023 K1 Biochemistry K1 Cell Biology K1 Pharmacology K1 Science Policy K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 various pain models K1 related side effects K1 potent analgesic responses K1 managing nociceptive pain K1 biological parameters even K1 7 ± 5 K1 dual μor agonist K1 developing safer opioids K1 6 ± 0 K1 μor agonism activity K1 promising lead compound K1 4x </ b K1 1 </ sub K1 μor agonism K1 k </ K1 classical opioids K1 6 nm K1 shown promise K1 reduced opioid K1 raising concern K1 r antagonist K1 r antagonism K1 optimal compound K1 new class K1 high dosage K1 findings suggest K1 excellent selectivity K1 depth studies K1 >< sub K1 2 nm JF doi:10.1021/acs.jmedchem.3c01637.s001 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.3c01637.s001 DO https://doi.org/10.1021/acs.jmedchem.3c01637.s001 SF ELIB - SuUB Bremen
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