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1 Ergebnisse
1
Discovery of a Highly Potent and Selective MYOF Inhibitor w..:
Haijun Gu
;
Ting Zhang
;
Tian Guan
...
doi:10.1021/acs.jmedchem.3c01639.s002. , 2023
Link:
https://doi.org/10.1021/acs.jmedchem.3c01639.s002
RT Journal T1
Discovery of a Highly Potent and Selective MYOF Inhibitor with Improved Water Solubility for the Treatment of Gastric Cancer
UL https://suche.suub.uni-bremen.de/peid=base-ftdeakinunifig:oai:figshare.com:article_24756569&Exemplar=1&LAN=DE A1 Haijun Gu A1 Ting Zhang A1 Tian Guan A1 Min Wu A1 Shen Li A1 Yunqi Li A1 Mengmeng Guo A1 Lin Zhang A1 Yangrui Peng A1 Dazhao Mi A1 Mingyao Liu A1 Zhengfang Yi A1 Yihua Chen YR 2023 K1 Biophysics K1 Biochemistry K1 Medicine K1 Cell Biology K1 Pharmacology K1 Cancer K1 Space Science K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 significantly improved compared K1 poor physicochemical properties K1 gastric cancer myoferlin K1 emerging therapeutic target K1 gastric cancer cells K1 selective myof inhibitor K1 improved water solubility K1 hj445a </ b K1 50 </ sub K1 water solubility K1 vivo </ K1 k </ K1 </ sub K1 various cancers K1 regulating exocytosis K1 preclinical studies K1 potently repressed K1 optimized based K1 optimal compound K1 novel range K1 myof inhibitors K1 mkn45 cells K1 lead compound K1 highly potent K1 fold enhancement K1 dependent manner K1 colony formation K1 c2d domain K1 >< sub K1 17 μm K1 14 μm JF doi:10.1021/acs.jmedchem.3c01639.s002 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.3c01639.s002 DO https://doi.org/10.1021/acs.jmedchem.3c01639.s002 SF ELIB - SuUB Bremen
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