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1 Ergebnisse
1
Structural Fusion of Natural and Synthetic Ligand Features ..:
Gustave Adouvi
;
Felix Nawa
;
Marco Ballarotto
...
doi:10.1021/acs.jmedchem.3c01435.s002. , 2023
Link:
https://doi.org/10.1021/acs.jmedchem.3c01435.s002
RT Journal T1
Structural Fusion of Natural and Synthetic Ligand Features Boosts RXR Agonist Potency
UL https://suche.suub.uni-bremen.de/peid=base-ftdeakinunifig:oai:figshare.com:article_24777869&Exemplar=1&LAN=DE A1 Gustave Adouvi A1 Felix Nawa A1 Marco Ballarotto A1 Lorena Andrea Rüger A1 Loris Knümann A1 Till Kasch A1 Silvia Arifi A1 Manfred Schubert-Zsilavecz A1 Sabine Willems A1 Julian A. Marschner A1 Jörg Pabel A1 Daniel Merk YR 2023 K1 Biochemistry K1 Genetics K1 Molecular Biology K1 Pharmacology K1 Biotechnology K1 Sociology K1 Hematology K1 Computational Biology K1 Chemical Sciences not elsewhere classified K1 varying substitution patterns K1 unexplored therapeutic potential K1 retinoid x receptors K1 remarkably boosted potency K1 poor physicochemical properties K1 critical ionic contact K1 binding site arginine K1 assay interference compounds K1 derived rxr ligands K1 natural ligand motif K1 structural fusion K1 profound effects K1 insufficient specificity K1 improved tools K1 endogenous vitamin K1 character enabled K1 bioisosteric replacement K1 apoptosis regulation K1 agonist activity K1 acrylic acid JF doi:10.1021/acs.jmedchem.3c01435.s002 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.3c01435.s002 DO https://doi.org/10.1021/acs.jmedchem.3c01435.s002 SF ELIB - SuUB Bremen
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