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1 Ergebnisse
1
ZIKV Inhibitors Based on Pyrazolo[3,4‑ d ]pyridazine-7-one ..:
Quang De Tran
;
Cuong Quoc Nguyen
;
Quang Le Dang
...
doi:10.1021/acsomega.3c06612.s001. , 1753
Link:
https://doi.org/10.1021/acsomega.3c06612.s001
RT Journal T1
ZIKV Inhibitors Based on Pyrazolo[3,4‑ d ]pyridazine-7-one Core: Rational Design, In Vitro Evaluation, and Theoretical Studies
UL https://suche.suub.uni-bremen.de/peid=base-ftdeakinunifig:oai:figshare.com:article_24810830&Exemplar=1&LAN=DE A1 Quang De Tran A1 Cuong Quoc Nguyen A1 Quang Le Dang A1 Thi Hong Minh Nguyen A1 Bui Thi Buu Hue A1 Minh Uyen Thi Le A1 Nguyen Trong Tuan A1 Nguyen Quoc Chau Thanh A1 Tran Thanh Men A1 Pham Minh Quan A1 Nguyen Duy Tuan A1 Thai Thi Cam A1 Nguyen Thi Thu Thuy A1 Vu Thi Bich Hau A1 Tran Duy Binh A1 Hong Phuong Nguyen YR 1753 K1 Biochemistry K1 Microbiology K1 Pharmacology K1 Immunology K1 Cancer K1 Virology K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 Information Systems not elsewhere classified K1 top 20 hits K1 synthesized 16 derivatives K1 molecular dynamics simulations K1 cause birth defects K1 based phenotypic assay K1 antimicrobial lead compounds K1 2 – 100 K1 protease via redocking K1 maximal effective concentration K1 zikv inhibitors based K1 9b </ b K1 19a </ b K1 zikv infection utilizing K1 pyrazolo [ 3 K1 4 μm ) K1 tyr161 ) K1 prospective inhibitors K1 ns3 protease K1 cytotoxic concentration K1 vitro </ K1 zikv drugs K1 zikv activity K1 zika virus K1 theoretical studies K1 strongly bound K1 selectivity index K1 rational design K1 pharmacophore model K1 one scaffold K1 one core K1 noncompetitive inhibitor K1 medical organizations K1 also targeted K1 >] pyridazine K1 >] pyridazine K1 6 μm K1 4 ‑< K1 4 -< K1 3 μg JF doi:10.1021/acsomega.3c06612.s001 LK http://dx.doi.org/https://doi.org/10.1021/acsomega.3c06612.s001 DO https://doi.org/10.1021/acsomega.3c06612.s001 SF ELIB - SuUB Bremen
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