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Compound screening cascade and the development and use of a..:
Frances M. Bashore
;
Vittorio L. Katis
;
Yuhong Du
...
doi:10.1371/journal.pone.0293548.g003. , 2024
Link:
https://doi.org/10.1371/journal.pone.0293548.g003
RT Journal T1
Compound screening cascade and the development and use of a biochemical TR-FRET assay to evaluate inhibition of the PPI between SYK-tSH2 and the FCERG1G p-ITAM peptide
UL https://suche.suub.uni-bremen.de/peid=base-ftdeakinunifig:oai:figshare.com:article_25228466&Exemplar=1&LAN=DE A1 Frances M. Bashore A1 Vittorio L. Katis A1 Yuhong Du A1 Arunima Sikdar A1 Dongxue Wang A1 William J. Bradshaw A1 Karolina A. Rygiel A1 Tina M. Leisner A1 Rod Chalk A1 Swati Mishra A1 C. Andrew Williams A1 Opher Gileadi A1 Paul E. Brennan A1 Jesse C. Wiley A1 Jake Gockley A1 Gregory A. Cary A1 Gregory W. Carter A1 Jessica E. Young A1 Kenneth H. Pearce A1 Haian Fu A1 Alison D. Axtman YR 2024 K1 Biophysics K1 Biochemistry K1 Cell Biology K1 Molecular Biology K1 Neuroscience K1 Pharmacology K1 Biotechnology K1 Immunology K1 Developmental Biology K1 Infectious Diseases K1 Plant Biology K1 Virology K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 tandem sh2 domains K1 compounds lack selectivity K1 based activation motif K1 alzheimer &# 8217 K1 doubly phosphorylated itam K1 since syk activation K1 fc receptor complexes K1 exacerbate ad pathology K1 itam </ p K1 fc receptor K1 itam ) K1 throughput screen K1 syk interacts K1 small molecules K1 putative targets K1 orthogonally assessed K1 immunoreceptor tyrosine K1 developed biochemical K1 covalent inhibitors K1 biophysical assays K1 ad patients JF doi:10.1371/journal.pone.0293548.g003 LK http://dx.doi.org/https://doi.org/10.1371/journal.pone.0293548.g003 DO https://doi.org/10.1371/journal.pone.0293548.g003 SF ELIB - SuUB Bremen
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