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1 Ergebnisse
1
Structure-Based Design of Novel G‑Protein-Coupled Receptor ..:
Zhenzhen Zhou
;
Weifeng Zhang
;
Fabao Zhao
...
doi:10.1021/acs.jmedchem.4c00195.s003. , 2024
Link:
https://doi.org/10.1021/acs.jmedchem.4c00195.s003
RT Journal T1
Structure-Based Design of Novel G‑Protein-Coupled Receptor TAAR1 Agonists as Potential Antipsychotic Drug Candidates
UL https://suche.suub.uni-bremen.de/peid=base-ftdeakinunifig:oai:figshare.com:article_25305702&Exemplar=1&LAN=DE A1 Zhenzhen Zhou A1 Weifeng Zhang A1 Fabao Zhao A1 Yanying Sun A1 Na Wang A1 Jie Cheng A1 Peng Zhan A1 Fan Yang A1 Jin-Peng Sun A1 Xinyong Liu A1 Dongwei Kang YR 2024 K1 Biophysics K1 Biochemistry K1 Molecular Biology K1 Neuroscience K1 Pharmacology K1 Biotechnology K1 Science Policy K1 Mental Health K1 significantly alleviated mk K1 novel drug candidate K1 existing available antipsychotics K1 containing metabolites without K1 seriously undesirable effects K1 sensing endogenous amine K1 novel taar1 agonists K1 pathway activation property K1 associated receptor 1 K1 taar1 activation pocket K1 q </ sub K1 6e </ b K1 2 </ sub K1 pathway activation K1 </ sub K1 trace amine K1 side effects K1 f </ K1 potent taar1 K1 >< sub K1 structural analysis K1 safety properties K1 rodent models K1 ideal target K1 designed based K1 cognitive impairment K1 antischizophrenia drugs K1 39 %) K1 31 h JF doi:10.1021/acs.jmedchem.4c00195.s003 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.4c00195.s003 DO https://doi.org/10.1021/acs.jmedchem.4c00195.s003 SF ELIB - SuUB Bremen
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