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1 Ergebnisse
1
MARC1 pLOF variants show association with reduced liver fat..:
Eriks Smagris
;
Lisa M. Shihanian
;
Ivory J. Mintah
...
doi:10.1371/journal.pgen.1011179.s012. , 2024
Link:
https://doi.org/10.1371/journal.pgen.1011179.s012
RT Journal T1
MARC1 pLOF variants show association with reduced liver fat and protection from various etiology liver diseases
UL https://suche.suub.uni-bremen.de/peid=base-ftdeakinunifig:oai:figshare.com:article_25337581&Exemplar=1&LAN=DE A1 Eriks Smagris A1 Lisa M. Shihanian A1 Ivory J. Mintah A1 Parnian Bigdelou A1 Yuliya Livson A1 Heather Brown A1 Niek Verweij A1 Charleen Hunt A1 Reid O'Brien Johnson A1 Tyler J. Greer A1 Suzanne A. Hartford A1 George Hindy A1 Luanluan Sun A1 Jonas B. Nielsen A1 Gabor Halasz A1 Luca A. Lotta A1 Andrew J. Murphy A1 Mark W. Sleeman A1 Viktoria Gusarova YR 2024 K1 Biochemistry K1 Genetics K1 Cancer K1 Virology K1 Environmental Sciences not elsewhere classified K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 five ancestry groups K1 lower hepatic fat K1 hepatic triglyceride accumulation K1 wide association study K1 wide association studies K1 div >< p K1 suggesting marc1 inhibition K1 recent human genome K1 deletion may lead K1 marc1 physiological function K1 mouse </ p K1 marc1 </ K1 hepatic cells K1 vitro studies K1 study found K1 function variants K1 > K1 p K1 marc1 plays K1 recapitulated earlier K1 phenotype similar K1 paralogue marc2 K1 observed phenotype K1 mouse liver K1 minor role K1 major difference K1 liver phenotype K1 liver inflammation K1 liver enzymes K1 findings highlight K1 divergent role K1 aberrant localization K1 000 individuals JF doi:10.1371/journal.pgen.1011179.s012 LK http://dx.doi.org/https://doi.org/10.1371/journal.pgen.1011179.s012 DO https://doi.org/10.1371/journal.pgen.1011179.s012 SF ELIB - SuUB Bremen
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