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Mechanistic modelling of tyrosine recombination reveals key..:

Jack E. Bowyer ; Deboki Chakravarti ; Wilson W. Wong.
https://digital-library.theiet.org/content/journals/10.1049/enb.2019.0020. , 2020

Link: https://doi.org/10.1049/enb.2019.0020

RT Journal
T1 <Title>Mechanistic modelling of tyrosine recombination reveals key parameters determining the performance of a CAR T cell switching circuit</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftdoajarticles:oai:doaj.org_article:53138d4c7d29466fb5d54aaab9de8cc7&Exemplar=1&LAN=DE
				
A1 Jack E. Bowyer
A1 Deboki Chakravarti
A1 Wilson W. Wong
A1 Declan G. Bates
PB Wiley
YR 2020
K1 molecular biophysics
K1 gene therapy
K1 biochemistry
K1 drugs
K1 genetic engineering
K1 biomedical materials
K1 tumours
K1 dna
K1 enzymes
K1 cancer
K1 cellular biophysics
K1 statistical approximation approaches
K1 system parameters
K1 optimal switch performance
K1 switching response
K1 inducer drug 4-oht
K1 flpo recombinase
K1 mechanistic modelling
K1 tyrosine recombination
K1 car t cell
K1 inducible genetic switches
K1 tyrosine recombinase-based dna excision
K1 chimeric antigen receptor t cell activity
K1 cancer immunotherapy
K1 increased stability
K1 tyrosine recombinases
K1 inversion–excision circuit design
K1 mechanistic mathematical model
K1 Biology (General)
K1 QH301-705.5
JF https://digital-library.theiet.org/content/journals/10.1049/enb.2019.0020
LK http://dx.doi.org/https://doi.org/10.1049/enb.2019.0020
DO https://doi.org/10.1049/enb.2019.0020
SF ELIB - SuUB Bremen

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