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Reducing systems biology models to derive mechanism-based d..:

Falkenhagen, U ; Knöchel, J ; Kloft, C.
Hamberg AK, Dahl ML, Barban M, Scordo MG, Wadelius M, Pengo V, Padrini R, Jonsson EN. A PK-PD model for predicting the impact of age, CYP2C9, and VKORC1 genotype on individualization of warfarin therapy. Clin Pharmacol Ther. 2007 Apr;81(4):529-38. DOI:10.1038/sj.clpt.6100084.  , 2021