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1 Ergebnisse
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Structure-Guided Design of a Highly Potent Partial RXR Agon..:
Max Lewandowski
;
Melania Carmina
;
Loris Knümann
...
doi:10.1021/acs.jmedchem.3c02095.s001. , 2024
Link:
https://doi.org/10.1021/acs.jmedchem.3c02095.s001
RT Journal T1
Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical Properties
UL https://suche.suub.uni-bremen.de/peid=base-ftgriffithunifig:oai:figshare.com:article_25024375&Exemplar=1&LAN=DE A1 Max Lewandowski A1 Melania Carmina A1 Loris Knümann A1 Minh Sai A1 Sabine Willems A1 Till Kasch A1 Julius Pollinger A1 Stefan Knapp A1 Julian A. Marschner A1 Apirat Chaikuad A1 Daniel Merk YR 2024 K1 Biophysics K1 Biochemistry K1 Molecular Biology K1 Pharmacology K1 Biotechnology K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 various indications beyond K1 nr2b1 – 3 K1 low nanomolar potency K1 line cancer treatment K1 hold therapeutic potential K1 promising therapeutic concept K1 improved rxr ligands K1 exploit rxr modulation K1 safety profiles K1 rigidization resulted K1 promising scaffold K1 novel pyrimidine K1 metabolic diseases K1 informed optimization K1 highly potent K1 guided design K1 cytotoxic activity K1 current role K1 cis </ K1 based ligand JF doi:10.1021/acs.jmedchem.3c02095.s001 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.3c02095.s001 DO https://doi.org/10.1021/acs.jmedchem.3c02095.s001 SF ELIB - SuUB Bremen
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