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1 Ergebnisse
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A Novel Leu-Enkephalin Prodrug Produces Pain-Relieving and ..:
Lukas Hohenwarter
;
Ernest Puil
;
Elham Rouhollahi
...
doi:10.1021/acs.molpharmaceut.3c00807.s001. , 2024
Link:
https://doi.org/10.1021/acs.molpharmaceut.3c00807.s001
RT Journal T1
A Novel Leu-Enkephalin Prodrug Produces Pain-Relieving and Antidepressant Effects
UL https://suche.suub.uni-bremen.de/peid=base-ftgriffithunifig:oai:figshare.com:article_25035623&Exemplar=1&LAN=DE A1 Lukas Hohenwarter A1 Ernest Puil A1 Elham Rouhollahi A1 Lennart Bohrmann A1 Shawna Lu A1 Katayoun Saatchi A1 Urs O. Häfeli A1 Alasdair Barr A1 Roland Böttger A1 K.K. DurgaRao Viswanadham A1 Shyh-Dar Li YR 2024 K1 Medicine K1 Genetics K1 Neuroscience K1 Physiology K1 Pharmacology K1 Biotechnology K1 Science Policy K1 Mental Health K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 significant healthcare problem K1 ramped hot plate K1 produces potent analgesia K1 minimal gastrointestinal inhibition K1 highly efficacious analgesics K1 delta opioid receptor K1 blood plasma exposure K1 like activity comparable K1 high proteolytic instability K1 limited treatment options K1 comorbid chronic pain K1 103 primarily resulted K1 prolonged antinociceptive efficacy K1 maximum antinociceptive K1 comparable dose K1 systemic administration K1 showed rapid K1 safe use K1 rapid development K1 likely conversion K1 less effective K1 high incidence K1 formalin test K1 effect relationship K1 controls pain K1 clinical usefulness K1 central effect K1 alleviating effect K1 103 ' K1 103 produced K1 103 compared JF doi:10.1021/acs.molpharmaceut.3c00807.s001 LK http://dx.doi.org/https://doi.org/10.1021/acs.molpharmaceut.3c00807.s001 DO https://doi.org/10.1021/acs.molpharmaceut.3c00807.s001 SF ELIB - SuUB Bremen
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