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Novel Cocrystal Structures of Peptide Antagonists Bound to ..:
Luis E. Gimenez
;
Charlotte Martin
;
Jing Yu
...
doi:10.1021/acs.jmedchem.3c01822.s001. , 1753
Link:
https://doi.org/10.1021/acs.jmedchem.3c01822.s001
RT Journal T1
Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design
UL https://suche.suub.uni-bremen.de/peid=base-ftgriffithunifig:oai:figshare.com:article_25207115&Exemplar=1&LAN=DE A1 Luis E. Gimenez A1 Charlotte Martin A1 Jing Yu A1 Charlie Hollanders A1 Ciria C. Hernandez A1 Yiran Wu A1 Deqiang Yao A1 Gye Won Han A1 Naima S. Dahir A1 Lijie Wu A1 Olivier Van der Poorten A1 Arthur Lamouroux A1 Morgane Mannes A1 Suwen Zhao A1 Dirk Tourwé A1 Raymond C. Stevens A1 Roger D. Cone A1 Steven Ballet YR 1753 K1 Biochemistry K1 Neuroscience K1 Physiology K1 Pharmacology K1 Immunology K1 Chemical Sciences not elsewhere classified K1 restrictive eating disorders K1 cell culture studies K1 6 </ sup K1 10 </ sup K1 treating cancer cachexia K1 selectivity sar study K1 g protein coupling K1 shu9119 </ b K1 complexed peptides led K1 934 </ b K1 sup >+</ sup K1 novel cocrystal structures K1 channel activation correlated K1 also investigated mc4 K1 peptide antagonists bound K1 treating positive K1 peptides differ K1 peptides activated K1 r selectivity K1 r coupling K1 tm2 domains K1 results highlight K1 ligands retained K1 inserting gly K1 increased feeding K1 antagonist activity K1 actively sought JF doi:10.1021/acs.jmedchem.3c01822.s001 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.3c01822.s001 DO https://doi.org/10.1021/acs.jmedchem.3c01822.s001 SF ELIB - SuUB Bremen
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