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Discovery and Characterization of a New Class of C5aR1 Anta..:
Francis Hubler
;
Dorte Renneberg
;
Hervé Siendt
...
doi:10.1021/acs.jmedchem.3c02375.s001. , 1753
Link:
https://doi.org/10.1021/acs.jmedchem.3c02375.s001
RT Journal T1
Discovery and Characterization of a New Class of C5aR1 Antagonists Showing In Vivo Activity
UL https://suche.suub.uni-bremen.de/peid=base-ftgriffithunifig:oai:figshare.com:article_25335020&Exemplar=1&LAN=DE A1 Francis Hubler A1 Dorte Renneberg A1 Hervé Siendt A1 Simon Stamm A1 Kurt Hilpert A1 Eva Caroff A1 Stephane Delahaye A1 Sylvie Froidevaux A1 Mark J. Murphy YR 1753 K1 Biochemistry K1 Cell Biology K1 Molecular Biology K1 Physiology K1 Pharmacology K1 Immunology K1 Cancer K1 Hematology K1 Infectious Diseases K1 Chemical Sciences not elsewhere classified K1 human whole blood K1 complement system ' K1 2 recruitment assay K1 chronic inflammatory disorders K1 component c5 protein K1 anaphylatoxin protein produced K1 c5ar1 antagonists showing K1 two leading compounds K1 two c5ar1 antagonists K1 50 </ sub K1 two compounds K1 inflammatory molecules K1 vivo </ K1 vitro </ K1 c5ar1 β K1 triggered interest K1 target engagement K1 rat model K1 primarily neutrophils K1 new class K1 large body K1 induced neutrophilia K1 dependent efficacy JF doi:10.1021/acs.jmedchem.3c02375.s001 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.3c02375.s001 DO https://doi.org/10.1021/acs.jmedchem.3c02375.s001 SF ELIB - SuUB Bremen
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