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An ESCRT module is required for neuron pruning:

Loncle, Nicolas ; Agromayor, Monica ; Martin-Serrano, Juan.
Loncle , N , Agromayor , M , Martin-Serrano , J & Williams , D W 2015 , ' An ESCRT module is required for neuron pruning ' , Scientific Reports , vol. 5 , no. 1 , 8461 . https://doi.org/10.1038/srep08461.  , 2015
Link: https://kclpure.kcl.ac.uk/portal/en/publications/an-es..