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The P323L substitution in the SARS-CoV-2 polymerase (NSP12)..:

Goldswain, H ; Dong, X ; Penrice-Randal, R...
https://eprints.whiterose.ac.uk/198930/1/The%20P323L%20substitution%20in%20the%20SARS-CoV-2%20polymerase%20%28NSP12%29%20confers%20a%20selective%20advantage%20during%20infection.pdf.  , 2023