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Shape does matter: short high-concentration exposure minimi..:

Rees, Vanessa Emily ; Bulitta, Jurgen Bernd ; Nation, Roger Leigh...
Rees , V E , Bulitta , J B , Nation , R L , Tsuji , B , Sorgel , F & Landersdorfer , C B 2015 , ' Shape does matter: short high-concentration exposure minimizes resistance emergence for fluoroquinolones in Pseudomonas aeruginosa ' , Journal of Antimicrobial Chemotherapy , vol. 70 , no. 3 , pp. 818 - 826 . https://doi.org/10.1093/jac/dku437.  , 2015