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1 Ergebnisse
1
AKT-mTORC1 reactivation is the dominant resistance driver f..:
Dunn, Shanade
;
Eberlein, Cath
;
Yu, Jason
...
Oncogene;41. , 2022
Link:
https://hdl.handle.net/11351/8698
RT Journal T1
AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors
UL https://suche.suub.uni-bremen.de/peid=base-ftscientia:oai:scientiasalut.gencat.cat:11351_8698&Exemplar=1&LAN=DE A1 Dunn, Shanade A1 Eberlein, Cath A1 Yu, Jason A1 Ong, Swee Hoe A1 Yelland, Urs A1 Serra Elizalde, Violeta A1 Gris Oliver, Albert PB Springer Nature YR 2022 K1 Mama - Càncer - Tractament K1 Medicaments antineoplàstics - Ús terapèutic K1 Resistència als medicaments K1 DISEASES::Neoplasms::Neoplasms by Site::Breast Neoplasms K1 Other subheadings::Other subheadings::Other subheadings::/drug therapy K1 PHENOMENA AND PROCESSES::Physiological Phenomena::Pharmacological and Toxicological Phenomena::Pharmacological Phenomena::Drug Resistance::Drug Resistance K1 Neoplasm K1 CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents K1 Other subheadings::Other subheadings::/therapeutic use K1 ENFERMEDADES::neoplasias::neoplasias por localización::neoplasias de la mama K1 Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia K1 FENÓMENOS Y PROCESOS::fenómenos fisiológicos::fenómenos farmacológicos y toxicológicos::fenómenos farmacológicos::resistencia a medicamentos::resistencia a los antineoplásicos K1 COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antineoplásicos K1 Otros calificadores::Otros calificadores::/uso terapéutico JF Oncogene;41 LK http://dx.doi.org/https://hdl.handle.net/11351/8698 DO https://hdl.handle.net/11351/8698 SF ELIB - SuUB Bremen
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