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Structural Assessment of Agonist Efficacy in the μ‑Opioid R..:

Adrián Ricarte (9991669) ; James A. R. Dalton (8543280) ; Jesús Giraldo (1558987)
https://figshare.com/articles/journal_contribution/Structural_Assessment_of_Agonist_Efficacy_in_the_Opioid_Receptor_Morphine_and_Fentanyl_Elicit_Different_Activation_Patterns/13580815. , 2021

Link: https://doi.org/10.1021/acs.jcim.0c00890.s001

RT Journal
T1 <Title>Structural Assessment of Agonist Efficacy in the μ‑Opioid Receptor: Morphine and Fentanyl Elicit Different Activation Patterns</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_13580815&Exemplar=1&LAN=DE
				
A1 Adrián Ricarte (9991669)
A1 James A. R. Dalton (8543280)
A1 Jesús Giraldo (1558987)
YR 2021
K1 Biophysics
K1 Biochemistry
K1 Cell Biology
K1 Neuroscience
K1 Pharmacology
K1 Evolutionary Biology
K1 Cancer
K1 Infectious Diseases
K1 Computational Biology
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 GPCR activation
K1 58 μ
K1 activates transmembrane
K1 fentanyl
K1 opioid epidemic
K1 μ s-length
K1 ligand binding
K1 Lys 235 5.39
K1 Met 153 3.36
K1 United States
K1 Gln 126 2.60
K1 MOR complexes
K1 TM 7
K1 μ- opioid receptor
K1 TM 6
K1 Activation Patterns
K1 compounds target
K1 activates TM 6
K1 TM 3
K1 intracellular receptor
K1 orthosteric pocket residues
K1 opioid drugs
K1 G protein-coupled receptor
K1 level ligand-specific receptor activity
K1 Agonist Efficacy
K1 signal transmission
K1 MD simulations
K1 sidechain
K1 Structural Assessment
K1 Tyr 150 3.33
K1 efficacy
K1 MOR antagonist naltrexone
K1 opiate-mediated analgesia
K1 Asp 149 3.32
K1 Fentanyl Elicit
K1 morphine
K1 fight pain
JF https://figshare.com/articles/journal_contribution/Structural_Assessment_of_Agonist_Efficacy_in_the_Opioid_Receptor_Morphine_and_Fentanyl_Elicit_Different_Activation_Patterns/13580815
LK http://dx.doi.org/https://doi.org/10.1021/acs.jcim.0c00890.s001
DO https://doi.org/10.1021/acs.jcim.0c00890.s001
SF ELIB - SuUB Bremen

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