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Engineering an Amine Transaminase for the Efficient Product..:

Scott J. Novick (1789494) ; Nikki Dellas (1270185) ; Ravi Garcia (10285153)...
https://figshare.com/articles/journal_contribution/Engineering_an_Amine_Transaminase_for_the_Efficient_Production_of_a_Chiral_Sacubitril_Precursor/14195143. , 2021

Link: https://doi.org/10.1021/acscatal.0c05450.s001

RT Journal
T1 <Title>Engineering an Amine Transaminase for the Efficient Production of a Chiral Sacubitril Precursor</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_14195143&Exemplar=1&LAN=DE
				
A1 Scott J. Novick (1789494)
A1 Nikki Dellas (1270185)
A1 Ravi Garcia (10285153)
A1 Charlene Ching (10285156)
A1 Abigail Bautista (10285159)
A1 David Homan (10285162)
A1 Oscar Alvizo (3297804)
A1 David Entwistle (5436857)
A1 Florian Kleinbeck (2364811)
A1 Thierry Schlama (2388259)
A1 Thomas Ruch (8850446)
YR 2021
K1 Biophysics
K1 Biochemistry
K1 Molecular Biology
K1 Pharmacology
K1 Biotechnology
K1 Evolutionary Biology
K1 Infectious Diseases
K1 Chemical Sciences not elsewhere classified
K1 Chiral Sacubitril Precursor
K1 trace activity
K1 Efficient Production
K1 enzyme variants
K1 substrate
K1 2 M
K1 reaction temperatures
K1 5 days
K1 chiral precursor
K1 11 rounds
K1 sacubitril
K1 product diastereomeric purity
K1 enzyme evolution
K1 isopropylamine concentrations
K1 CDX
K1 enzyme variant
K1 amine transaminase
K1 undesired diastereoisomer
K1 reaction times
K1 24 h
K1 blockbuster heart failure drug Entresto
K1 process robustness
JF https://figshare.com/articles/journal_contribution/Engineering_an_Amine_Transaminase_for_the_Efficient_Production_of_a_Chiral_Sacubitril_Precursor/14195143
LK http://dx.doi.org/https://doi.org/10.1021/acscatal.0c05450.s001
DO https://doi.org/10.1021/acscatal.0c05450.s001
SF ELIB - SuUB Bremen

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