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1 Ergebnisse
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Modulation of the Passive Permeability of Semipeptidic Macr..:
Christian Comeau (9044807)
;
Benjamin Ries (10344237)
;
Thomas Stadelmann (10344240)
...
https://figshare.com/articles/journal_contribution/Modulation_of_the_Passive_Permeability_of_Semipeptidic_Macrocycles_N-_and_C_Methylations_Fine-Tune_Conformation_and_Properties/14262042. , 1753
Link:
https://doi.org/10.1021/acs.jmedchem.0c02036.s002
RT Journal T1
Modulation of the Passive Permeability of Semipeptidic Macrocycles: N- and C‑Methylations Fine-Tune Conformation and Properties
UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_14262042&Exemplar=1&LAN=DE A1 Christian Comeau (9044807) A1 Benjamin Ries (10344237) A1 Thomas Stadelmann (10344240) A1 Jacob Tremblay (10344243) A1 Sylvain Poulet (10344246) A1 Ulrike Fröhlich (10344249) A1 Jérôme Côté (1514596) A1 Pierre-Luc Boudreault (1346352) A1 Rabeb Mouna Derbali (10344252) A1 Philippe Sarret (238472) A1 Michel Grandbois (481525) A1 Grégoire Leclair (1929895) A1 Sereina Riniker (1450804) A1 Éric Marsault (1634674) YR 1753 K1 Biophysics K1 Biochemistry K1 Genetics K1 Pharmacology K1 Biotechnology K1 Cancer K1 Space Science K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 results show K1 Properties Incorporating K1 36 compounds K1 semipeptidic macrocycle backbone K1 nonpeptidic linker K1 impact permeability K1 methyl placements K1 alkyl linker K1 peptidic macrocycles K1 peptoid position K1 Semipeptidic Macrocycles K1 Passive Permeability K1 offer hypotheses K1 Caco -2 assays K1 peptidic drugs K1 PAMPA K1 peptide-to-peptoid substitution K1 influence K1 pharmacokinetic profiles K1 membrane permeability assay K1 NMR measurements K1 methyl substitution K1 dynamics simulations JF https://figshare.com/articles/journal_contribution/Modulation_of_the_Passive_Permeability_of_Semipeptidic_Macrocycles_N-_and_C_Methylations_Fine-Tune_Conformation_and_Properties/14262042 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.0c02036.s002 DO https://doi.org/10.1021/acs.jmedchem.0c02036.s002 SF ELIB - SuUB Bremen
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