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Targeting KRAS Mutant Cancers via Combination Treatment: Di..:

Malcolm P. Huestis (10493092) ; Darlene Dela Cruz (10493095) ; Antonio G. DiPasquale (1274730)...
https://figshare.com/articles/dataset/Targeting_KRAS_Mutant_Cancers_via_Combination_Treatment_Discovery_of_a_5_Fluoro-4-_3_i_H_i_quinazolinone_Aryl_Urea_pan-RAF_Kinase_Inhibitor/14336944. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.0c02085.s001

RT Journal
T1 <Title>Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5‑Fluoro-4-(3 H )‑quinazolinone Aryl Urea pan-RAF Kinase Inhibitor</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_14336944&Exemplar=1&LAN=DE
				
A1 Malcolm P. Huestis (10493092)
A1 Darlene Dela Cruz (10493095)
A1 Antonio G. DiPasquale (1274730)
A1 Matthew R. Durk (7052600)
A1 Charles Eigenbrot (1346406)
A1 Paul Gibbons (114343)
A1 Alberto Gobbi (1508113)
A1 Thomas L. Hunsaker (3160575)
A1 Hank La (438084)
A1 Dennis H. Leung (2106256)
A1 Wendy Liu (2057074)
A1 Shiva Malek (1346394)
A1 Mark Merchant (282025)
A1 John G. Moffat (413533)
A1 Christine S. Muli (10493098)
A1 Christine J. Orr (10493101)
A1 Brendan T. Parr (2342548)
A1 Frances Shanahan (655624)
A1 Christopher J. Sneeringer (10493104)
A1 Weiru Wang (640332)
A1 Ivana Yen (1346373)
A1 Jianping Yin (557395)
A1 Michael Siu (1503160)
A1 Joachim Rudolph (1464982)
YR 2021
K1 Biophysics
K1 Biochemistry
K1 Medicine
K1 Cell Biology
K1 Molecular Biology
K1 Pharmacology
K1 Cancer
K1 Hematology
K1 Infectious Diseases
K1 Virology
K1 Space Science
K1 Chemical Sciences not elsewhere classified
K1 Physical Sciences not elsewhere classified
K1 kinase selectivity
K1 vivo evaluation
K1 solubility
K1 Combination Treatment
K1 MEK inhibitor cobimetinib
K1 tumor growth inhibition
K1 NH functionality
K1 pathway inhibition
K1 Strategic substitution
K1 fluoroquinazolinone hinge-binding motif
K1 xenograft mouse model
K1 C 5 position
K1 RAF-specific residue interactions
K1 aryl urea RAF inhibitors
K1 type II pan-RAF inhibitor GNE -0749
K1 Targeting KRAS Mutant Cancers
JF https://figshare.com/articles/dataset/Targeting_KRAS_Mutant_Cancers_via_Combination_Treatment_Discovery_of_a_5_Fluoro-4-_3_i_H_i_quinazolinone_Aryl_Urea_pan-RAF_Kinase_Inhibitor/14336944
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.0c02085.s001
DO https://doi.org/10.1021/acs.jmedchem.0c02085.s001
SF ELIB - SuUB Bremen

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