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Discovery and Optimization of 2 H ‑1λ 2 ‑Pyridin-2-one Inhi..:

Jason M. Rohde (10531594) ; Surendra Karavadhi (6051887) ; Rajan Pragani (105058)...
https://figshare.com/articles/journal_contribution/Discovery_and_Optimization_of_2_i_H_i_1_sup_2_sup_Pyridin-2-one_Inhibitors_of_Mutant_Isocitrate_Dehydrogenase_1_for_the_Treatment_of_Cancer/14378707. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c00019.s002

RT Journal
T1 <Title>Discovery and Optimization of 2 H ‑1λ 2 ‑Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_14378707&Exemplar=1&LAN=DE
				
A1 Jason M. Rohde (10531594)
A1 Surendra Karavadhi (6051887)
A1 Rajan Pragani (105058)
A1 Li Liu (75607)
A1 Yuhong Fang (3032253)
A1 Weihe Zhang (1332372)
A1 Andrew McIver (10531597)
A1 Hongchao Zheng (531059)
A1 Qingyang Liu (1508776)
A1 Mindy I. Davis (105040)
A1 Daniel J. Urban (9424971)
A1 Tobie D. Lee (4583152)
A1 Dorian M. Cheff (4583155)
A1 Melinda Hollingshead (107715)
A1 Mark J. Henderson (811537)
A1 Natalia J. Martinez (3090897)
A1 Kyle R. Brimacombe (1860301)
A1 Adam Yasgar (134148)
A1 Wei Zhao (14321)
A1 Carleen Klumpp-Thomas (3371171)
A1 Sam Michael (105053)
A1 Joseph Covey (10531600)
A1 William J. Moore (1464922)
A1 Gordon M. Stott (4583158)
A1 Zhuyin Li (105078)
A1 Anton Simeonov (85099)
A1 Ajit Jadhav (85100)
A1 Stephen Frye (2210458)
A1 Matthew D. Hall (316516)
A1 Min Shen (68726)
A1 Xiaodong Wang (66801)
A1 Samarjit Patnaik (1878463)
A1 Matthew B. Boxer (1860292)
YR 2021
K1 Medicine
K1 Cell Biology
K1 Molecular Biology
K1 Pharmacology
K1 Biotechnology
K1 Cancer
K1 Hematology
K1 Virology
K1 Chemical Sciences not elsewhere classified
K1 48 h
K1 tumoral concentrations
K1 dose
K1 myeloid leukemia
K1 Cancer Neomorphic mutations
K1 Pyridin
K1 screening
K1 SAR
K1 mIDH 1-U mouse model
K1 R 132C
K1 Mutant Isocitrate Dehydrogenase 1
K1 R 132H
K1 malignancy
K1 isocitrate dehydrogenase
K1 glioma
K1 isocitrate dehydrogenase 1
K1 series
K1 ivosidenib
K1 chemistry campaign
K1 Optimization
K1 post
K1 SM 5637
K1 quinoline
K1 dimethyl
K1 dione
K1 oncogenic
K1 pyrid -2-one mIDH 1 inhibitors
K1 -1λ
K1 Inhibitor
K1 effort
K1 mg
K1 2- HG concentrations
K1 NCATS
K1 NSC 791985
K1 atropisomer
K1 Systematic
K1 drug AG -120
JF https://figshare.com/articles/journal_contribution/Discovery_and_Optimization_of_2_i_H_i_1_sup_2_sup_Pyridin-2-one_Inhibitors_of_Mutant_Isocitrate_Dehydrogenase_1_for_the_Treatment_of_Cancer/14378707
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c00019.s002
DO https://doi.org/10.1021/acs.jmedchem.1c00019.s002
SF ELIB - SuUB Bremen

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