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SMO interacts with free PKA-C subunits rather than PKA holo..:

Corvin D. Arveseth (10688311) ; John T. Happ (10688314) ; Danielle S. Hedeen (10688317)...
https://figshare.com/articles/figure/SMO_interacts_with_free_PKA-C_subunits_rather_than_PKA_holoenzymes_/14470561.  , 2021