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Design and Synthesis of Highly Selective Brain Penetrant p3..:

Niklas M. Tormählen (10783636) ; Mariella Martorelli (10783639) ; Annette Kuhn (3494771)...
https://figshare.com/articles/journal_contribution/Design_and_Synthesis_of_Highly_Selective_Brain_Penetrant_p38_Mitogen-Activated_Protein_Kinase_Inhibitors/14575333. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.0c01773.s001

RT Journal
T1 <Title>Design and Synthesis of Highly Selective Brain Penetrant p38α Mitogen-Activated Protein Kinase Inhibitors</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_14575333&Exemplar=1&LAN=DE
				
A1 Niklas M. Tormählen (10783636)
A1 Mariella Martorelli (10783639)
A1 Annette Kuhn (3494771)
A1 Florian Maier (1861138)
A1 Jamil Guezguez (1459330)
A1 Michael Burnet (1459333)
A1 Wolfgang Albrecht (2035297)
A1 Stefan A. Laufer (128881)
A1 Pierre Koch (560721)
YR 2021
K1 Biochemistry
K1 Medicine
K1 Cell Biology
K1 Genetics
K1 Molecular Biology
K1 Neuroscience
K1 Physiology
K1 Pharmacology
K1 Biotechnology
K1 Immunology
K1 Infectious Diseases
K1 Plant Biology
K1 Virology
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 methyl ester prodrugs
K1 acid transporters
K1 IL -6
K1 novel Skepinone-based p 38α MAP kin
K1 p 38α-MAP metabolically
K1 Skepinone-N counterpart
K1 5.5 nM
K1 dibenzo
K1 Selective Brain Penetrant p 38α Mit
K1 12 nM
K1 TNF -α production
K1 carboxy analogs
K1 difluorophenyl
K1 kinase activation modulates cytokin
K1 Compound 70
K1 annulene
K1 cell-based assays
K1 brain-to-plasma ratios
K1 -3-carboxamido
K1 mouse brain
K1 IC
K1 brain-to-plasma ratio
JF https://figshare.com/articles/journal_contribution/Design_and_Synthesis_of_Highly_Selective_Brain_Penetrant_p38_Mitogen-Activated_Protein_Kinase_Inhibitors/14575333
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.0c01773.s001
DO https://doi.org/10.1021/acs.jmedchem.0c01773.s001
SF ELIB - SuUB Bremen

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