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Systematic Optimization of Potent and Orally Bioavailable P..:

Biswajit Kundu (1736323) ; Deblina Raychaudhuri (7145210) ; Ayan Mukherjee (2847836)...
https://figshare.com/articles/journal_contribution/Systematic_Optimization_of_Potent_and_Orally_Bioavailable_Purine_Scaffold_as_a_Dual_Inhibitor_of_Toll-Like_Receptors_7_and_9/14806471. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c00532.s001

RT Journal
T1 <Title>Systematic Optimization of Potent and Orally Bioavailable Purine Scaffold as a Dual Inhibitor of Toll-Like Receptors 7 and 9</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_14806471&Exemplar=1&LAN=DE
				
A1 Biswajit Kundu (1736323)
A1 Deblina Raychaudhuri (7145210)
A1 Ayan Mukherjee (2847836)
A1 Bishnu Prasad Sinha (7145216)
A1 Dipika Sarkar (10992517)
A1 Purbita Bandopadhyay (7145228)
A1 Sourav Pal (768862)
A1 Nirmal Das (10992520)
A1 Debdeep Dey (9662577)
A1 Kantubhukta Ramarao (10992523)
A1 Kasireddy Nagireddy (10992526)
A1 Dipyaman Ganguly (241339)
A1 Arindam Talukdar (2062678)
YR 2021
K1 Biochemistry
K1 Medicine
K1 Pharmacology
K1 Biotechnology
K1 Immunology
K1 Cancer
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 vivo pharmacokinetic studies
K1 TLR 7
K1 TLR 9
K1 mouse TLR 9
K1 IC 50 values
K1 2.66 μ M
K1 small-molecule TLR 7
K1 Toll-Like Receptors 7
K1 Isothermal titration calorimetry
K1 Orally Bioavailable Purine Scaffold
K1 TLR 9 antagonists
K1 compound 29
K1 N 9 substitutions
K1 vivo antagonism efficacy
JF https://figshare.com/articles/journal_contribution/Systematic_Optimization_of_Potent_and_Orally_Bioavailable_Purine_Scaffold_as_a_Dual_Inhibitor_of_Toll-Like_Receptors_7_and_9/14806471
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c00532.s001
DO https://doi.org/10.1021/acs.jmedchem.1c00532.s001
SF ELIB - SuUB Bremen

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