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Discovery of M 3 Antagonist-PDE4 Inhibitor Dual Pharmacolog..:

Elisabetta Armani (1845475) ; Andrea Rizzi (1845439) ; Carmelida Capaldi (1845460)...
https://figshare.com/articles/dataset/Discovery_of_M_sub_3_sub_Antagonist-PDE4_Inhibitor_Dual_Pharmacology_Molecules_for_the_Treatment_of_Chronic_Obstructive_Pulmonary_Disease/14806748. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c00204.s002

RT Journal
T1 <Title>Discovery of M 3 Antagonist-PDE4 Inhibitor Dual Pharmacology Molecules for the Treatment of Chronic Obstructive Pulmonary Disease</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_14806748&Exemplar=1&LAN=DE
				
A1 Elisabetta Armani (1845475)
A1 Andrea Rizzi (1845439)
A1 Carmelida Capaldi (1845460)
A1 Renato De Fanti (4685659)
A1 Maurizio Delcanale (1845487)
A1 Gino Villetti (155284)
A1 Gessica Marchini (4685662)
A1 Anna Rita Pisano (10993211)
A1 Vanessa Pitozzi (10993214)
A1 Maria Gloria Pittelli (10993217)
A1 Marcello Trevisani (10993220)
A1 Michela Salvadori (10993223)
A1 Valentina Cenacchi (1845451)
A1 Paola Puccini (1845493)
A1 Francesco Amadei (1845448)
A1 Alice Pappani (4023374)
A1 Maurizio Civelli (1845466)
A1 Riccardo Patacchini (144063)
A1 Charles A.G. Baker-Glenn (10993226)
A1 Hervé Van de Poël (1937056)
A1 Wesley P. Blackaby (2259880)
A1 Kevin Nash (337750)
A1 Gabriele Amari (1845463)
YR 2021
K1 Biochemistry
K1 Medicine
K1 Pharmacology
K1 Biotechnology
K1 Infectious Diseases
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 chemical series
K1 anti-inflammatory efficacy
K1 muscarinic scaffolds
K1 nanomolar PDE 4 inhibition
K1 SAR optimization
K1 transmembrane M 3 receptor
K1 M 3 antagonist-PDE 4 inhibitor
K1 Chronic Obstructive Pulmonary Disease
K1 compound 92
K1 M 3 nanomolar affinity
K1 intratracheal administration
K1 TNF α release
K1 rat trachea contraction
K1 PDE 4 scaffold
K1 vivo efficacy
K1 muscarinic scaffold
K1 anti-bronchospastic efficacy
K1 intracellular PDE 4 enzyme
K1 CHF -6001 series
K1 MAPI
K1 inhaled treatment
K1 Pharmacology Molecules
K1 inflammation assays
JF https://figshare.com/articles/dataset/Discovery_of_M_sub_3_sub_Antagonist-PDE4_Inhibitor_Dual_Pharmacology_Molecules_for_the_Treatment_of_Chronic_Obstructive_Pulmonary_Disease/14806748
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c00204.s002
DO https://doi.org/10.1021/acs.jmedchem.1c00204.s002
SF ELIB - SuUB Bremen

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