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Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bi..:

Robert E. Trout (11054298) ; Allison Zulli (11054301) ; Eugen Mesaros (11054304)...
https://figshare.com/articles/journal_contribution/Discovery_of_VNRX-7145_VNRX-5236_Etzadroxil_An_Orally_Bioavailable_Lactamase_Inhibitor_for_Enterobacterales_Expressing_Ambler_Class_A_C_and_D_Enzymes/14887989. , 1753

Link: https://doi.org/10.1021/acs.jmedchem.1c00437.s002

RT Journal
T1 <Title>Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bioavailable β‑Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_14887989&Exemplar=1&LAN=DE
				
A1 Robert E. Trout (11054298)
A1 Allison Zulli (11054301)
A1 Eugen Mesaros (11054304)
A1 Randy W. Jackson (3028935)
A1 Steven Boyd (4583962)
A1 Bin Liu (5899)
A1 Jodie Hamrick (11054307)
A1 Denis Daigle (11054310)
A1 Cassandra L. Chatwin (11054313)
A1 Kaitlyn John (11054316)
A1 Lisa McLaughlin (11054319)
A1 Susan M. Cusick (8129040)
A1 William J. Weiss (230468)
A1 Mark E. Pulse (4967758)
A1 Daniel C. Pevear (2497423)
A1 Greg Moeck (11054322)
A1 Luigi Xerri (8129043)
A1 Christopher J. Burns (685703)
YR 1753
K1 Biochemistry
K1 Medicine
K1 Microbiology
K1 Pharmacology
K1 Biotechnology
K1 Immunology
K1 Cancer
K1 Infectious Diseases
K1 Space Science
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 outpatient treatment
K1 prodrug
K1 extended-spectrum β- lactamases
K1 boronic acid-containing β- lactamas
K1 D Enzymes
K1 ED
K1 antimicrobial resistance mechanism
K1 difficult-to-treat bacteria
K1 β- lactamase enzymes
K1 class D oxacillinases
K1 class C cephalosporinases
K1 vivo studies
K1 cephalosporin antibiotic ceftibuten
K1 Enterobacterale
K1 hospital Emergency Department
K1 Ambler Class
K1 Gram-negative bacteria
K1 iterative program
K1 VNRX -7145
K1 Lead optimization
K1 parenteral antibiotic therapy
JF https://figshare.com/articles/journal_contribution/Discovery_of_VNRX-7145_VNRX-5236_Etzadroxil_An_Orally_Bioavailable_Lactamase_Inhibitor_for_Enterobacterales_Expressing_Ambler_Class_A_C_and_D_Enzymes/14887989
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c00437.s002
DO https://doi.org/10.1021/acs.jmedchem.1c00437.s002
SF ELIB - SuUB Bremen

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