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The relative tube formation of a tumoroid culture is stable..:

Sarah Line Bring Truelsen (11091170) ; Nabi Mousavi (11091173) ; Haoche Wei (4780050)...
https://figshare.com/articles/figure/The_relative_tube_formation_of_a_tumoroid_culture_is_stable_between_independent_experiments_/14926331.  , 2021