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Design and Synthesis of Novel Spiro Derivatives as Potent a..:

Shuhei Ikeda (2380180) ; Hideyuki Sugiyama (3062157) ; Hidekazu Tokuhara (3013323)...
https://figshare.com/articles/dataset/Design_and_Synthesis_of_Novel_Spiro_Derivatives_as_Potent_and_Reversible_Monoacylglycerol_Lipase_MAGL_Inhibitors_Bioisosteric_Transformation_from_3_Oxo-3_4-dihydro_2_i_H_i_benzo_i_b_i_1_4_oxazin-6-yl_Moiety/15082714. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c00432.s001

RT Journal
T1 <Title>Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3‑Oxo-3,4-dihydro‑2 H ‑benzo[ b ][1,4]oxazin-6-yl Moiety</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_15082714&Exemplar=1&LAN=DE
				
A1 Shuhei Ikeda (2380180)
A1 Hideyuki Sugiyama (3062157)
A1 Hidekazu Tokuhara (3013323)
A1 Masataka Murakami (2330896)
A1 Minoru Nakamura (398375)
A1 Yuya Oguro (1992457)
A1 Jumpei Aida (1399486)
A1 Nao Morishita (1992430)
A1 Satoshi Sogabe (1399567)
A1 Douglas R. Dougan (2342836)
A1 Sean C. Gay (2002897)
A1 Ling Qin (68169)
A1 Naoto Arimura (416442)
A1 Yasuko Takahashi (2488249)
A1 Masako Sasaki (1746523)
A1 Yusuke Kamada (1786591)
A1 Kazunobu Aoyama (1786444)
A1 Kouya Kimoto (11210110)
A1 Makoto Kamata (2084602)
YR 2021
K1 Biophysics
K1 Biochemistry
K1 Cell Biology
K1 Molecular Biology
K1 Physiology
K1 Pharmacology
K1 Biotechnology
K1 Plant Biology
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 Information Systems not elsewhere classified
K1 compound 1
K1 reversible-type inhibitor
K1 novel bioisosteres
K1 4 f
K1 novel spiro chemical series
K1 system-related diseases
K1 lipophilic ligand efficiency
K1 co-crystal structure
K1 binding mode
K1 LLE
K1 Novel Spiro Derivatives
K1 arachidonic acid decrease
K1 monoacylglycerol lipase
K1 Arg 57
K1 MAGL inhibitors
K1 structure-based drug discovery
K1 Bioisosteric Transformation
K1 spiro scaffolds
K1 MAGL inhibitor
K1 Reversible Monoacylglycerol Lipase
K1 hand side
K1 IC
K1 SBDD
JF https://figshare.com/articles/dataset/Design_and_Synthesis_of_Novel_Spiro_Derivatives_as_Potent_and_Reversible_Monoacylglycerol_Lipase_MAGL_Inhibitors_Bioisosteric_Transformation_from_3_Oxo-3_4-dihydro_2_i_H_i_benzo_i_b_i_1_4_oxazin-6-yl_Moiety/15082714
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c00432.s001
DO https://doi.org/10.1021/acs.jmedchem.1c00432.s001
SF ELIB - SuUB Bremen

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