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Discovery of a First-in-Class Inhibitor of the PRMT5–Substr..:

David C. McKinney (1551352) ; Brian J. McMillan (11224604) ; Matthew J. Ranaghan (1309221)...
https://figshare.com/articles/dataset/Discovery_of_a_First-in-Class_Inhibitor_of_the_PRMT5_Substrate_Adaptor_Interaction/15097832. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c00507.s002

RT Journal
T1 <Title>Discovery of a First-in-Class Inhibitor of the PRMT5–Substrate Adaptor Interaction</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_15097832&Exemplar=1&LAN=DE
				
A1 David C. McKinney (1551352)
A1 Brian J. McMillan (11224604)
A1 Matthew J. Ranaghan (1309221)
A1 Jamie A. Moroco (11224607)
A1 Merissa Brousseau (11224610)
A1 Zachary Mullin-Bernstein (11224613)
A1 Meghan O'Keefe (11224616)
A1 Patrick McCarren (1313079)
A1 Michael F. Mesleh (1577284)
A1 Kathleen M. Mulvaney (8311938)
A1 Foxy Robinson (11224619)
A1 Ritu Singh (660180)
A1 Besnik Bajrami (2331208)
A1 Florence F. Wagner (445656)
A1 Robert Hilgraf (2695921)
A1 Martin J. Drysdale (2188942)
A1 Arthur J. Campbell (2167885)
A1 Adam Skepner (4962658)
A1 David E. Timm (3925361)
A1 Dale Porter (1992982)
A1 Virendar K. Kaushik (11224622)
A1 William R. Sellers (9353775)
A1 Alessandra Ianari (9353772)
YR 2021
K1 Biophysics
K1 Biochemistry
K1 Microbiology
K1 Pharmacology
K1 Infectious Diseases
K1 Chemical Sciences not elsewhere classified
K1 First-in-Class Inhibitor
K1 PBM-dependent PRMT 5 activities
K1 covalent bond
K1 substrate methylation
K1 SAPs share
K1 molecule inhibitors
K1 novel PRMT 5 inhibitors
K1 PRMT 5
K1 PRMT 5 binding motif
K1 mediates binding
K1 substrate adaptor proteins
K1 MTAP-deleted cancer cells
K1 PRMT 5. Optimization
K1 cysteine 278
K1 spliceosome complexes
K1 first-in-class PBM-competitive inhi
K1 compound series
K1 BRD 0639
K1 pyridazinone group
K1 action studies
K1 PRMT 5 substrates
JF https://figshare.com/articles/dataset/Discovery_of_a_First-in-Class_Inhibitor_of_the_PRMT5_Substrate_Adaptor_Interaction/15097832
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c00507.s002
DO https://doi.org/10.1021/acs.jmedchem.1c00507.s002
SF ELIB - SuUB Bremen

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