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Discovery of ASTX029, A Clinical Candidate Which Modulates ..:

Tom D. Heightman (236769) ; Valerio Berdini (1668088) ; Luke Bevan (2621935)...
https://figshare.com/articles/journal_contribution/Discovery_of_ASTX029_A_Clinical_Candidate_Which_Modulates_the_Phosphorylation_and_Catalytic_Activity_of_ERK1_2/16444618. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c00905.s001

RT Journal
T1 <Title>Discovery of ASTX029, A Clinical Candidate Which Modulates the Phosphorylation and Catalytic Activity of ERK1/2</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_16444618&Exemplar=1&LAN=DE
				
A1 Tom D. Heightman (236769)
A1 Valerio Berdini (1668088)
A1 Luke Bevan (2621935)
A1 Ildiko M. Buck (1541779)
A1 Maria G. Carr (2272138)
A1 Aurélie Courtin (5322428)
A1 Joseph E. Coyle (1668076)
A1 James E. H. Day (11335396)
A1 Charlotte East (5322422)
A1 Lynsey Fazal (1269375)
A1 Charlotte M. Griffiths-Jones (4044440)
A1 Steven Howard (760049)
A1 Justyna Kucia-Tran (11335399)
A1 Vanessa Martins (824485)
A1 Sandra Muench (5322446)
A1 Joanne M. Munck (1668070)
A1 David Norton (1697866)
A1 Marc O'Reilly (2396422)
A1 Nicholas Palmer (5962949)
A1 Puja Pathuri (1871719)
A1 Torren M. Peakman (2465449)
A1 Michael Reader (1541824)
A1 David C. Rees (1541794)
A1 Sharna J. Rich (1541815)
A1 Alpesh Shah (11335402)
A1 Nicola G. Wallis (2457757)
A1 Hugh Walton (5322440)
A1 Nicola E. Wilsher (1541797)
A1 Alison J.-A. Woolford (2074540)
A1 Michael Cooke (5322437)
A1 David Cousin (5322425)
A1 Stuart Onions (5322452)
A1 Jonathan Shannon (3847888)
A1 John Watts (5322434)
A1 Christopher W. Murray (1668094)
YR 2021
K1 Biochemistry
K1 Medicine
K1 Cell Biology
K1 Genetics
K1 Pharmacology
K1 Immunology
K1 Developmental Biology
K1 Cancer
K1 Infectious Diseases
K1 Virology
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 mitogen-activated protein kinase pa
K1 candidate ASTX 029
K1 structure-guided optimization
K1 CYP 3A metabolism
K1 ERK
K1 Catalytic Activity
K1 pharmacokinetic properties
K1 Clinical Candidate
K1 ASTX 029
K1 chemistry campaign
K1 B-Raf proto-oncogene
K1 drives tumor growth
K1 physicochemical properties
JF https://figshare.com/articles/journal_contribution/Discovery_of_ASTX029_A_Clinical_Candidate_Which_Modulates_the_Phosphorylation_and_Catalytic_Activity_of_ERK1_2/16444618
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c00905.s001
DO https://doi.org/10.1021/acs.jmedchem.1c00905.s001
SF ELIB - SuUB Bremen

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