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Structure-Based Optimization of Quinazolines as Cruzain and..:

Elany Barbosa da Silva (11357125) ; Débora A. Rocha (11357128) ; Isadora S. Fortes (11357131)...
https://figshare.com/articles/journal_contribution/Structure-Based_Optimization_of_Quinazolines_as_Cruzain_and_i_Tbr_i_CATL_Inhibitors/16543921. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c01151.s001

RT Journal
T1 <Title>Structure-Based Optimization of Quinazolines as Cruzain and Tbr CATL Inhibitors</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_16543921&Exemplar=1&LAN=DE
				
A1 Elany Barbosa da Silva (11357125)
A1 Débora A. Rocha (11357128)
A1 Isadora S. Fortes (11357131)
A1 Wenqian Yang (1947496)
A1 Ludovica Monti (1484272)
A1 Jair L. Siqueira-Neto (92312)
A1 Conor R. Caffrey (113916)
A1 James McKerrow (138952)
A1 Saulo F. Andrade (1603876)
A1 Rafaela S. Ferreira (1271616)
YR 2021
K1 Biochemistry
K1 Medicine
K1 Pharmacology
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 Physical Sciences not elsewhere classified
K1 mid micromolar concentrations
K1 human african trypanosomiasis
K1 4 μm )
K1 7 </ b
K1 1a </ b
K1 tbr </
K1 n </
K1 k </
K1 </ sub
K1 trypanosoma cruzi
K1 trypanosoma brucei
K1 therapeutic targets
K1 study )
K1 rhodesain )
K1 quinazoline core
K1 physicochemical properties
K1 original publication
K1 maintain potency
K1 known inhibitors
K1 fourteen compounds
K1 cidal activity
K1 chagas disease
K1 biological evaluation
K1 based design
K1 >< sup
K1 >< sub
K1 22 analogs
JF https://figshare.com/articles/journal_contribution/Structure-Based_Optimization_of_Quinazolines_as_Cruzain_and_i_Tbr_i_CATL_Inhibitors/16543921
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01151.s001
DO https://doi.org/10.1021/acs.jmedchem.1c01151.s001
SF ELIB - SuUB Bremen

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