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1 Ergebnisse
1
Discovery of BPR1R024, an Orally Active and Selective CSF1R..:
Kun-Hung Lee (11520724)
;
Wan-Ching Yen (11520727)
;
Wen-Hsing Lin (208256)
...
https://figshare.com/articles/dataset/Discovery_of_BPR1R024_an_Orally_Active_and_Selective_CSF1R_Inhibitor_that_Exhibits_Antitumor_and_Immunomodulatory_Activity_in_a_Murine_Colon_Tumor_Model/16734943. , 1753
Link:
https://doi.org/10.1021/acs.jmedchem.1c01006.s002
RT Journal T1
Discovery of BPR1R024, an Orally Active and Selective CSF1R Inhibitor that Exhibits Antitumor and Immunomodulatory Activity in a Murine Colon Tumor Model
UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_16734943&Exemplar=1&LAN=DE A1 Kun-Hung Lee (11520724) A1 Wan-Ching Yen (11520727) A1 Wen-Hsing Lin (208256) A1 Pei-Chen Wang (6575789) A1 You-Liang Lai (11520730) A1 Yu-Chieh Su (138988) A1 Chun-Yu Chang (380014) A1 Cai-Syuan Wu (11520733) A1 Yu-Chen Huang (1926214) A1 Chen-Ming Yang (542457) A1 Ling-Hui Chou (507465) A1 Teng-Kuang Yeh (208258) A1 Chiung-Tong Chen (33535) A1 Chuan Shih (1434997) A1 Hsing-Pang Hsieh (139595) YR 1753 K1 Biochemistry K1 Medicine K1 Cell Biology K1 Genetics K1 Pharmacology K1 Biotechnology K1 Immunology K1 Cancer K1 Chemical Sciences not elsewhere classified K1 molecular docking revealed K1 chain extension strategy K1 additional nonclassical hydrogen K1 > K1 oral administration K1 like macrophage survival K1 like macrophage growth K1 selective csf1r inhibitors K1 selective csf1r inhibitor K1 csf1r potency enhancement K1 csf1r hinge region K1 bpr1k871 (< b K1 aurora kinase b K1 12 </ b K1 immunosuppressive tumor microenvironment K1 50 </ sub K1 vivo </ K1 associated macrophage K1 b activities K1 unique 7 K1 structural studies K1 stimulating factor K1 promising target K1 orally active K1 minimal effect K1 mesylate delayed K1 m2 ratio K1 increased m1 K1 immunomodulatory activity K1 exhibits antitumor K1 driven optimization K1 cancer immunotherapy K1 back pockets K1 antitumor m1 K1 aminoquinazoline scaffold K1 53 nm K1 1 receptor JF https://figshare.com/articles/dataset/Discovery_of_BPR1R024_an_Orally_Active_and_Selective_CSF1R_Inhibitor_that_Exhibits_Antitumor_and_Immunomodulatory_Activity_in_a_Murine_Colon_Tumor_Model/16734943 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01006.s002 DO https://doi.org/10.1021/acs.jmedchem.1c01006.s002 SF ELIB - SuUB Bremen
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