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Computational Enzyme Stabilization Can Affect Folding Energ..:
Klara Markova (6639851)
;
Antonin Kunka (5745425)
;
Klaudia Chmelova (11539195)
...
https://figshare.com/articles/journal_contribution/Computational_Enzyme_Stabilization_Can_Affect_Folding_Energy_Landscapes_and_Lead_to_Catalytically_Enhanced_Domain-Swapped_Dimers/16775737. , 2021
Link:
https://doi.org/10.1021/acscatal.1c03343.s001
RT Journal T1
Computational Enzyme Stabilization Can Affect Folding Energy Landscapes and Lead to Catalytically Enhanced Domain-Swapped Dimers
UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_16775737&Exemplar=1&LAN=DE A1 Klara Markova (6639851) A1 Antonin Kunka (5745425) A1 Klaudia Chmelova (11539195) A1 Martin Havlasek (11539198) A1 Petra Babkova (3205713) A1 Sérgio M. Marques (2360983) A1 Michal Vasina (6938837) A1 Joan Planas-Iglesias (1452142) A1 Radka Chaloupkova (492929) A1 David Bednar (821277) A1 Zbynek Prokop (821281) A1 Jiri Damborsky (1322766) A1 Martin Marek (463593) YR 2021 K1 Biophysics K1 Biochemistry K1 Evolutionary Biology K1 Virology K1 Computational Biology K1 Chemical Sciences not elsewhere classified K1 Physical Sciences not elsewhere classified K1 Information Systems not elsewhere classified K1 unfolding experiments showed K1 stabilizing mutations might K1 nascent polypeptide follows K1 local energy minima K1 linking mass spectrometry K1 increased catalytic rate K1 global energy minimum K1 force field calculations K1 establish secondary interfaces K1 crystallographic structures revealed K1 activate cryptic hinge K1 5 ° c K1 23 ° c K1 hydrolase enzyme (< K1 like energy landscape K1 swapped intermediates trapped K1 stabilize native proteins K1 catalytically enhanced domain K1 computational enzyme stabilization K1 computational stabilization K1 enzyme depends K1 like monomers K1 unique three K1 unique example K1 swapped dimers K1 substrate inhibition K1 ray scattering K1 monomeric α K1 loop regions K1 irreversibly converted K1 intertwined protomers K1 increasingly employed K1 generation biocatalysts K1 folding process K1 encoded algorithms K1 eleven single K1 dimensional structure K1 data obtained K1 confirmed experimentally K1 biotechnology applications K1 angle x K1 >< sub JF https://figshare.com/articles/journal_contribution/Computational_Enzyme_Stabilization_Can_Affect_Folding_Energy_Landscapes_and_Lead_to_Catalytically_Enhanced_Domain-Swapped_Dimers/16775737 LK http://dx.doi.org/https://doi.org/10.1021/acscatal.1c03343.s001 DO https://doi.org/10.1021/acscatal.1c03343.s001 SF ELIB - SuUB Bremen
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