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Discovery of a Series of 7‑Azaindoles as Potent and Highly ..:

Bernard Barlaam (1638841) ; Chris De Savi (9761188) ; Allan Dishington (1710121)...
https://figshare.com/articles/journal_contribution/Discovery_of_a_Series_of_7_Azaindoles_as_Potent_and_Highly_Selective_CDK9_Inhibitors_for_Transient_Target_Engagement/16811145. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c01249.s001

RT Journal
T1 <Title>Discovery of a Series of 7‑Azaindoles as Potent and Highly Selective CDK9 Inhibitors for Transient Target Engagement</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_16811145&Exemplar=1&LAN=DE
				
A1 Bernard Barlaam (1638841)
A1 Chris De Savi (9761188)
A1 Allan Dishington (1710121)
A1 Lisa Drew (1981495)
A1 Andrew D. Ferguson (1427719)
A1 Douglas Ferguson (6244943)
A1 Chungang Gu (1638805)
A1 Sudhir Hande (9436524)
A1 Lorraine Hassall (1507771)
A1 Janet Hawkins (2114890)
A1 Alexander W. Hird (1864699)
A1 Jane Holmes (5164544)
A1 Michelle L. Lamb (1545151)
A1 Andrew S. Lister (9436530)
A1 Thomas M. McGuire (1638829)
A1 Jane E. Moore (1456585)
A1 Nichole O'Connell (1427731)
A1 Anil Patel (1638817)
A1 Kurt G. Pike (1638820)
A1 Ujjal Sarkar (603912)
A1 Wenlin Shao (2472)
A1 Darren Stead (2178408)
A1 Jeffrey G. Varnes (2499496)
A1 Melissa M. Vasbinder (1864678)
A1 Lei Wang (6656)
A1 Liangwei Wu (9761203)
A1 Lin Xue (826042)
A1 Bin Yang (103252)
A1 Tieguang Yao (9761206)
YR 2021
K1 Biochemistry
K1 Medicine
K1 Cell Biology
K1 Pharmacology
K1 Biotechnology
K1 Evolutionary Biology
K1 Cancer
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 Information Systems not elsewhere classified
K1 suitable physical properties
K1 pharmacokinetic properties led
K1 6 </ b
K1 38 </ b
K1 2 </ b
K1 7 ‑ azaindoles
K1 selective cdk9 inhibitors
K1 vivo </
K1 highly selective
K1 cdk9 led
K1 transient inhibition
K1 short half
K1 screening hit
K1 optimization focusing
K1 intravenous administration
K1 information gained
K1 hematological malignancies
K1 crystal structure
K1 based lead
K1 azabenzimidazoles identified
K1 achieve profound
JF https://figshare.com/articles/journal_contribution/Discovery_of_a_Series_of_7_Azaindoles_as_Potent_and_Highly_Selective_CDK9_Inhibitors_for_Transient_Target_Engagement/16811145
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01249.s001
DO https://doi.org/10.1021/acs.jmedchem.1c01249.s001
SF ELIB - SuUB Bremen

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