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Discovery of IHMT-EZH2-115 as a Potent and Selective Enhanc..:

Bin Zhou (84959) ; Xiaofei Liang (843086) ; Husheng Mei (11581149)...
https://figshare.com/articles/dataset/Discovery_of_IHMT-EZH2-115_as_a_Potent_and_Selective_Enhancer_of_Zeste_Homolog_2_EZH2_Inhibitor_for_the_Treatment_of_B-Cell_Lymphomas/16832778. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c01154.s003

RT Journal
T1 <Title>Discovery of IHMT-EZH2-115 as a Potent and Selective Enhancer of Zeste Homolog 2 (EZH2) Inhibitor for the Treatment of B-Cell Lymphomas</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_16832778&Exemplar=1&LAN=DE
				
A1 Bin Zhou (84959)
A1 Xiaofei Liang (843086)
A1 Husheng Mei (11581149)
A1 Shuang Qi (1502860)
A1 Zongru Jiang (3745834)
A1 Aoli Wang (1319265)
A1 Fengming Zou (1586605)
A1 Qingwang Liu (791358)
A1 Juan Liu (6492)
A1 Wenliang Wang (1233804)
A1 Chen Hu (317374)
A1 Yongfei Chen (1319262)
A1 Zuowei Wang (333190)
A1 Beilei Wang (298371)
A1 Li Wang (15202)
A1 Jing Liu (38537)
A1 Qingsong Liu (381059)
YR 2021
K1 Biochemistry
K1 Cell Biology
K1 Genetics
K1 Molecular Biology
K1 Pharmacology
K1 Cancer
K1 Chemical Sciences not elsewhere classified
K1 zeste homologue 2
K1 zeste homolog 2
K1 cellular levels led
K1 apparent inhibitory activity
K1 30 μm )
K1 go related gene
K1 epz6438 (< b
K1 29 </ b
K1 3 nm )
K1 showed better efficacy
K1 ezh2 mutant cancers
K1 50 </ sub
K1 1 </ b
K1 1 nm
K1 h3k27 )
K1 ́- go
K1 solid tumors
K1 oral administration
K1 inhibited ezh2
K1 human ether
K1 histone methyltransferases
K1 high selectivity
K1 hematologic malignancies
K1 ezh2 y641f
K1 ezh2 mutants
K1 cell lymphomas
K1 catalyzes methylation
K1 catalytic subunit
K1 biochemical assay
K1 binding model
K1 analogues aiming
K1 422 cell
JF https://figshare.com/articles/dataset/Discovery_of_IHMT-EZH2-115_as_a_Potent_and_Selective_Enhancer_of_Zeste_Homolog_2_EZH2_Inhibitor_for_the_Treatment_of_B-Cell_Lymphomas/16832778
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01154.s003
DO https://doi.org/10.1021/acs.jmedchem.1c01154.s003
SF ELIB - SuUB Bremen

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