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Discovery of Modified Amidate (ProTide) Prodrugs of Tenofov..:

Filip Kalčic (11623690) ; Michala Zgarbová (11623693) ; Jan Hodek (3848179)...
https://figshare.com/articles/journal_contribution/Discovery_of_Modified_Amidate_ProTide_Prodrugs_of_Tenofovir_with_Enhanced_Antiviral_Properties/16903405. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c01444.s001

RT Journal
T1 <Title>Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_16903405&Exemplar=1&LAN=DE
				
A1 Filip Kalčic (11623690)
A1 Michala Zgarbová (11623693)
A1 Jan Hodek (3848179)
A1 Karel Chalupský (11623696)
A1 Martin Dračínský (1398268)
A1 Alexandra Dvořáková (11623699)
A1 Timotej Strmeň (11623702)
A1 Jaroslav Šebestík (1275918)
A1 Ondřej Baszczyňski (6668468)
A1 Jan Weber (299007)
A1 Helena Mertlíková-Kaiserová (1600819)
A1 Zlatko Janeba (1585501)
YR 2021
K1 Medicine
K1 Cell Biology
K1 Molecular Biology
K1 Pharmacology
K1 Immunology
K1 Infectious Diseases
K1 Virology
K1 Space Science
K1 Biological Sciences not elsewhere classified
K1 Chemical Sciences not elsewhere classified
K1 substantially higher levels
K1 promising results provide
K1 phenol moiety present
K1 highly potent antivirals
K1 enhanced antiviral properties
K1 digit picomolar ec
K1 chiral hplc column
K1 based prodrug reached
K1 afford diastereomeric mixtures
K1 released tenofovir inside
K1 50 </ sub
K1 study describes
K1 strong foundation
K1 resolved using
K1 potential utility
K1 one pot
K1 nearly 300
K1 modified amidate
K1 human lymphocytes
K1 human hepatocytes
K1 efficient tyrosine
K1 86 %)
JF https://figshare.com/articles/journal_contribution/Discovery_of_Modified_Amidate_ProTide_Prodrugs_of_Tenofovir_with_Enhanced_Antiviral_Properties/16903405
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01444.s001
DO https://doi.org/10.1021/acs.jmedchem.1c01444.s001
SF ELIB - SuUB Bremen

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