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Pre-Existing Oxidative Stress Creates a Docking-Ready Confo..:
Carl J. Fossum (9311752)
;
Bethany F. Laatsch (11746187)
;
Harrison R. Lowater (11746190)
...
https://figshare.com/articles/journal_contribution/Pre-Existing_Oxidative_Stress_Creates_a_Docking-Ready_Conformation_of_the_SARS-CoV_2_Receptor-Binding_Domain/17068388. , 2021
Link:
https://doi.org/10.1021/acsbiomedchemau.1c00040.s001
RT Journal T1
Pre-Existing Oxidative Stress Creates a Docking-Ready Conformation of the SARS-CoV‑2 Receptor-Binding Domain
UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_17068388&Exemplar=1&LAN=DE A1 Carl J. Fossum (9311752) A1 Bethany F. Laatsch (11746187) A1 Harrison R. Lowater (11746190) A1 Alex W. Narkiewicz-Jodko (11746193) A1 Leo Lonzarich (11746196) A1 Sanchita Hati (1308198) A1 Sudeep Bhattacharyya (1308201) YR 2021 K1 Biophysics K1 Biochemistry K1 Molecular Biology K1 Immunology K1 Cancer K1 Computational Biology K1 Biological Sciences not elsewhere classified K1 Chemical Sciences not elsewhere classified K1 Physical Sciences not elsewhere classified K1 spectacular conformational change K1 present simulations revealed K1 offering future clues K1 intrinsic conformational dynamics K1 alternate therapeutic possibilities K1 present study demonstrates K1 existing oxidative stress K1 converting enzyme ii K1 2 spike protein K1 disulfide bonds preserves K1 binding domain occurs K1 study demonstrates K1 oxidative stress K1 spike protein K1 reduction occurs K1 disulfide bonds K1 protein partners K1 peptidase domain K1 binding domain K1 thiol conversion K1 taken together K1 structural complementarity K1 significantly altered K1 ready conformation K1 native complex K1 limited impact K1 implicit solvation K1 fully impairs K1 evolved structures K1 dependent changes K1 conformation ready K1 binding affinity K1 bending motion K1 already bound JF https://figshare.com/articles/journal_contribution/Pre-Existing_Oxidative_Stress_Creates_a_Docking-Ready_Conformation_of_the_SARS-CoV_2_Receptor-Binding_Domain/17068388 LK http://dx.doi.org/https://doi.org/10.1021/acsbiomedchemau.1c00040.s001 DO https://doi.org/10.1021/acsbiomedchemau.1c00040.s001 SF ELIB - SuUB Bremen
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