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1 Ergebnisse
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Discovery of a Novel Potent and Selective Calcium Release-A..:
Nilesh Raghunath Khedkar (11768497)
;
Nageswara Rao Irlapatti (11768500)
;
Disha Dadke (11768503)
...
https://figshare.com/articles/journal_contribution/Discovery_of_a_Novel_Potent_and_Selective_Calcium_Release-Activated_Calcium_Channel_Inhibitor_2_6-Difluoro_i_N_i_2_-methyl-3_-_4-methyl-5-oxo-4_5-dihydro-1_3_4-oxadiazol-2-yl_-_1_1_-biphenyl_-4-yl_benzamide_Structure_Activity_Relationship_a/17096695. , 2021
Link:
https://doi.org/10.1021/acs.jmedchem.1c01403.s001
RT Journal T1
Discovery of a Novel Potent and Selective Calcium Release-Activated Calcium Channel Inhibitor: 2,6-Difluoro‑ N ‑(2′-methyl-3′-(4-methyl-5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-[1,1′-biphenyl]-4-yl)benzamide. Structure–Activity Relationship and Preclinical Characterization
UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_17096695&Exemplar=1&LAN=DE A1 Nilesh Raghunath Khedkar (11768497) A1 Nageswara Rao Irlapatti (11768500) A1 Disha Dadke (11768503) A1 Vijay Kanoje (841839) A1 Zubair Shaikh (11768506) A1 Vijay Karche (11768509) A1 Vikas Shinde (1667995) A1 Gokul Deshmukh (11768512) A1 Amit Patil (1436473) A1 Santosh Jachak (11768515) A1 Samiron Phukan (2483575) A1 Praveenkumar Anidil Kizhakinagath (11768518) A1 Milind Gholve (9718948) A1 Trupti Bhankhede (11768521) A1 Jagadeesh Daler (8862353) A1 Harshal Narendra Nemade (11768524) A1 Sagar Budhe (8862368) A1 Himani Pareek (8862365) A1 Rajesh Yeshodharan (8862347) A1 Rajesh Gupta (65584) A1 Anil Kalia (8862344) A1 Dilip Pandey (8862380) A1 Akshaya Wagh (8862383) A1 Swaroop Kumar (11768527) A1 Vinod Patil (7932779) A1 Dipak Modi (7932782) A1 Nidhi Sharma (509997) A1 Prajakta Ahirrao (9718966) A1 Maneesh Mehta (7932776) A1 Hemant Kumar (2889176) A1 Prashant Nigade (7932773) A1 Kaustubh Tamane (9718957) A1 Sadanand Mallurwar (7932785) A1 Sandip Kuldharan (7932794) A1 Shashikant Pawar (8862386) A1 Gururaj Vishwase (11768530) A1 Sanjay Bokan (11768533) A1 Minakshi Singh (7932800) A1 Kumar Naik (11768536) A1 Sachin Ingawale (11768539) A1 Rajesh Shankar (11768542) A1 Prabakaran Kamalakannan (11768545) A1 Spinvin Venugopal (11768548) A1 Shaji K. George (2986455) A1 Kamlesh J. Padiya (2078722) A1 Kumar V. S. Nemmani (5347634) A1 Jaysagar Gundu (11768551) A1 Mandar Bhonde (9718984) A1 Lakshmi Narasimham (7932803) A1 Milind Sindkhedkar (11768554) A1 Chirag Shah (245746) A1 Neelima Sinha (648566) A1 Sharad Sharma (185231) A1 Dhananjay Bakhle (8038006) A1 Rajender Kumar Kamboj (7932806) A1 Venkata P. Palle (2139517) YR 2021 K1 Biochemistry K1 Medicine K1 Cell Biology K1 Neuroscience K1 Pharmacology K1 Immunology K1 Chemical Sciences not elsewhere classified K1 treating inflammatory diseases K1 sufficient safety margin K1 subsequent histopathological evaluation K1 several autoimmune diseases K1 remarkable pharmacokinetic profile K1 like rheumatoid arthritis K1 good target engagement K1 excellent safety profile K1 attractive therapeutic target K1 vivo ra models K1 selective calcium release K1 36 </ b K1 yl )-[ 1 K1 3 ′-( 4 K1 calcium release K1 ra ) K1 n </ K1 activated calcium K1 well characterized K1 tissues led K1 particular importance K1 oral administration K1 novel potent K1 human testing K1 difluoro ‑< K1 clinical candidate K1 cell function JF https://figshare.com/articles/journal_contribution/Discovery_of_a_Novel_Potent_and_Selective_Calcium_Release-Activated_Calcium_Channel_Inhibitor_2_6-Difluoro_i_N_i_2_-methyl-3_-_4-methyl-5-oxo-4_5-dihydro-1_3_4-oxadiazol-2-yl_-_1_1_-biphenyl_-4-yl_benzamide_Structure_Activity_Relationship_a/17096695 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01403.s001 DO https://doi.org/10.1021/acs.jmedchem.1c01403.s001 SF ELIB - SuUB Bremen
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