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Design, Synthesis, and Evaluation of Potent, Selective, and..:

Xufen Yu (1570180) ; Jia Xu (111777) ; Ling Xie (2026981)...
https://figshare.com/articles/dataset/Design_Synthesis_and_Evaluation_of_Potent_Selective_and_Bioavailable_AKT_Kinase_Degraders/17118481. , 2021

Link: https://doi.org/10.1021/acs.jmedchem.1c01476.s002

RT Journal
T1 <Title>Design, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase Degraders</Title>

UL https://suche.suub.uni-bremen.de/peid=base-ftsmithonian:oai:figshare.com:article_17118481&Exemplar=1&LAN=DE
				
A1 Xufen Yu (1570180)
A1 Jia Xu (111777)
A1 Ling Xie (2026981)
A1 Li Wang (15202)
A1 Yudao Shen (1476319)
A1 Kaitlyn M. Cahuzac (11786020)
A1 Xian Chen (107385)
A1 Jing Liu (38537)
A1 Ramon E. Parsons (11786023)
A1 Jian Jin (351142)
YR 2021
K1 Biochemistry
K1 Medicine
K1 Cell Biology
K1 Molecular Biology
K1 Neuroscience
K1 Pharmacology
K1 Immunology
K1 Science Policy
K1 Infectious Diseases
K1 Plant Biology
K1 Chemical Sciences not elsewhere classified
K1 numerous human cancers
K1 identified two novel
K1 e3 ligase ligands
K1 pi3k )/ akt
K1 inhibited downstream signaling
K1 akt binding moieties
K1 25 </ b
K1 13 </ b
K1 extensive sar studies
K1 two akt degraders
K1 signaling pathway
K1 various linkers
K1 strongly correlated
K1 phosphatidylinositol 3
K1 pathogenic functions
K1 ms170 )
K1 mammalian target
K1 investigate biological
K1 intraperitoneal injection
K1 critical node
K1 aberrant activation
JF https://figshare.com/articles/dataset/Design_Synthesis_and_Evaluation_of_Potent_Selective_and_Bioavailable_AKT_Kinase_Degraders/17118481
LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01476.s002
DO https://doi.org/10.1021/acs.jmedchem.1c01476.s002
SF ELIB - SuUB Bremen

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